Penn BIOL 404 - BIOL 404 - 2018 SPRING SYLLABUS (59 pages)

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BIOL 404 - 2018 SPRING SYLLABUS



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BIOL 404 - 2018 SPRING SYLLABUS

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Pages:
59
School:
University of Pennsylvania
Course:
Biol 404 - Immunobiology.
Unformatted text preview:

BIOLOGY 404 Basic Immunobiology SPRING 2018 IMPORTANT DATES FOR THE 2018 SPRING TERM January 10 Spring Term Classes Begin Mon classes on Wed January 15 Martin Luther King Jr Day no class January 29 Course Selection Period Ends February 16 Drop Period Ends March 3 11 Spring Term Break Saturday Sunday March 30 April 25 April 26 April 27 April 30 May 8 May 8 Last day to withdraw from a course Spring Term Classes End Reading Days Thursday Friday Final Examinations Monday Tuesday Spring Term Ends NUMBERS EMAILS Mike Cancro TAs 284 John Morgan 215 898 8067 office 215 898 6668 lab cancro pennmedicine upenn edu Glendon Wu glendon pennmedicine upenn edu Jamie Knox knoxjam pennmedicine upenn edu 2 BIOLOGY 404 BASIC IMMUNOBIOLOGY MONDAYS 6 30 to 9 10 PM COURSE GOALS The goals of this course are several First I hope to introduce you to basic principles and current concepts in the field of immunology Second I would like to stimulate your thinking especially from an experimental standpoint about how these principles and concepts are formed Finally I hope you will leave with a foundation that will enable you to learn more on your own through critical appraisal of the literature COURSE DESCRIPTION The course will begin with a general overview of immunity followed by in depth considerations of the underlying cellular molecular and genetic events Finally later discussions will focus upon more specialized issues in immunology such as disease states involving the immune system as well as particularly interesting problems in modern immunology EXAMS There will be two exams EACH WITH A TAKE HOME AND AN IN CLASS PORTION They will be primarily essay or brief answer questions including data interpretation and readings from the primary literature Take home exams will be distributed two weeks before the in class exams and must be turned in with the in class exam Take home exams will not be accepted late In toto the exams comprise 50 of your final grade SCHOLARLY PAPER Every student must write a scholarly review of some area of immunology in which they are interested The paper should be between ten and fourteen pages in length typed and double spaced It should be appropriately referenced from the primary literature including titles and complete pagination Your topic choice and an initial outline must be approved by me or one of TAs by as early as possible after the mid term THE PAPER IS DUE AT THE END OF THE MONDAY CLASS PERIOD TWO WEEKS BEFORE THE FINAL the day the second take home becomes available Check the class schedule for the exact date this semester After that 5 chips per day of tardiness will be deducted from your paper grade The paper comprises 25 of your final grade THREADED DISCUSSIONS DEBATES There will be five threaded discussion debate topics in each half of the course one per week You are expected to conscientiously contribute to these several times each week Your contributions do not have to be lengthy but they must be thoughtful clear and well reasoned These comprise 25 of your final grade QUIZZES There will be an optional quiz at the beginning of every session These are mainly for self evaluation and can only improve your final grade Each is worth 10 chips and will be corrected and returned by the next class Since these are optional extra credit no make ups are given I will replace your lowest mark including a zero for a missed class with a 10 SCHEDULE Each 3 hour session will be divided as follows Up to the first 15 minutes will be devoted to an open discussion of the previous lecture quiz questions The quiz 15 minutes will be given and collected Two one hour lectures will be given with a short break if there is time READINGS Required readings in the primary text are given in the table on page 5 I expect you to use these to strengthen your grasp and broaden your perspective on the concepts conveyed in class 3 TEXT The recommended text is Janeway s Immunobiology 9th edition published by Garland Press Copies are available in the University Bookstore or via Amazon com ATTENDANCE Attendance is not required although participation in the quizzes will allow us to determine if excessive absences might be the basis for poor performance and could mitigate against any special consideration if this is the case GRADING The following straight scale grading system will be used 97 A 87 89 B 77 79 C 93 96 A 83 86 B 73 76 C 90 2 A 80 85 B 70 72 C 70 D 60 F Throughout the course you may collect chips At the end you cash in your chips and your grade will be computed by taking your total chips and dividing by 4 If taking the course pass fail you must complete all required evaluative instruments i e both exams all threads debates and the paper and achieve a final score of 60 CHIP SOURCES AND MAXIMA QUIZZES There will be 11 optional quizzes If you choose to take them each is worth 10 chips At the end of the course 20 of your quiz chips are added to your other chips PRIOR TO division by 4 The maximum chips from quizzes are thus 110 X 20 or 22 the maximum the quizzes can add to your final grade is thus 5 5 If you miss a quiz you may get a copy for study purposes but as they are optional and can only improve your grade no make ups are given Your lowest quiz gets replaced with a 10 so if you miss one that s your give away perfect score PAPER Your scholarly paper will be worth 100 chips THREADED DISCUSSIONS DEBATES Each threaded discussion or debate is worth 10 chips There will be ten of these five in each half of the course so they are worth 100 chips altogether THESE ARE A QUARTER OF YOUR GRADE DON T blow them off EXAMS The in class portion of each exam is worth 55 chips The take home part of each exam is worth 45 chips SUMMARY OF CHIP SOURCES AND MAXIMA Quizzes 22 Paper 100 Exam I in class 55 Exam I take home 45 Exam II in class 55 Exam II take home 45 Threads Debates 100 MAX POSSIBLE TOTAL CHIPS 422 MAX POSSIBLE FINAL SCORE 105 5 422 4 4 SCHEDULE OF LECTURES AND TOPICS SESSIONS BEGIN PROMPTLY AT 6 30PM DATE JAN 10 JAN 22 JAN 29 LECTURE TOPIC INTRODUCTION TO BASIC IMMUNOLOGY KINETICS AND PROPERTIES OF IMMUNE REPSONSES ANTIBODY ANTIGEN INTERACTIONS MOLECULAR AND CELLULAR ELEMENTS OF IMMUNITY AB STRUCTURE FUNCTION CELLS AND TISUES OF THE IMMUNE SYSTEM CELLULAR AND MOLECULAR BASIS FOR SPECIFICITY RECEPTOR DIVERSITY IN LYMPHOID POPULATIONS Page 7 15 24 MOLECULAR BASIS FOR ANTIGEN RECEPTOR DIVERSITY FEB 5 HUMORAL RESPONSES AND EFFECTOR MECHANISMS NEUTRALIZATION OPSONIZATION COMPLEMENT 30 FEB 12 T A STRUCTURED REVIEW


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