DREXEL PSY 310 - Top Ten Discoveries in Psychopharmacology (3 pages)

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Top Ten Discoveries in Psychopharmacology



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Top Ten Discoveries in Psychopharmacology

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Pages:
3
School:
Drexel University
Course:
Psy 310 - Drugs & Human Behavior

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Top Ten Discoveries in Psychopharmacology Abused Substances and Psychotherapeutic Drugs Each discovery created a shift in paradigm could not be explained by current models paradigms and opened the door to a new line of study by opening the door to new paradigms 5 substance and abuse 5 psychotherapeutic drugs Drug Craving Can Be Learned When confronted with cues that in the past have been paired with the drug people and nonhuman animals dependent on drugs display evidence of craving intense urge to take drug and heightened drug withdrawal symptoms Opened up the study of Role of learning and experience in drug abuse Role of drug anticipatory responses in drug abuse tolerance and dependence Role of dopamine and other neurotransmitters in drug craving and withdrawal Shephard Siegel 1985 Abused Drugs Have Reinforcing Properties Self Administration A variety of abused drugs have reinforcing effects i e animals will press a lever in order to receive an injection of drug into the blood or into the brain drug induced self administration behavior Opened up the study of Predictability of abuse potential of a drug in humans through its ability to produce selfadministration reinforcing effects The role of specific neurotransmitters dopamine and anatomical substrates nucleus accumbens in the self administration reinforcing effects of abused drugs Weeks 1962 Abused Drugs Serve as Discriminative Stimuli Animals can learn to press a lever in the presence of a specific abused drug e g when heroin acts as the reinforced cue and withhold pressing the lever in a non drugged state or in the presence of a different drug state e g in the presence of amphetamine as the non reinforced cue Opened up the study of Comparing drugs with similar and dissimilar subjective effects in studies of cross tolerance among abused and non abused drugs Identifying and examining the neurochemical basis among similar and dissimilar drugs with abuse potential Alcohol Dependence Can Be Treated With Naltrexone or



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