UGA POUL 3000 - InflammationSGuide-2 (2 pages)

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InflammationSGuide-2



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InflammationSGuide-2

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Pages:
2
School:
University of Georgia
Course:
Poul 3000 - Avian Biomed Tech

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Inflammation 1 What are the five cardinal signs of inflammation 2 What is colloid osmotic pressure Hydrostatic pressure 3 What chemokine released by mast cells upon interaction with a pathogen contributes to increased hydrostatic pressure and localized edema 4 Why would you not want to get injured by a Punji stick or poop stick How could this contribute to more intense inflammation 5 Be familiar with the roles of the different inflammation mediators bradykinin C3 C5a Plasmin Thrombin Factor XII Hageman Factor bradykinin PGI2 prostacyclin 6 Know the kinin system and its pathway of activation 7 What is the difference between transudate and exudate 8 Role of prostaglandin E2 Leukotriene B4 histamine bradykinin in inflammation 9 Describe the process the leads to the emigration of leukocytes at the area of injury Be sure to include margination cytokines TNF IL 1 P selectins E selectins integrin diapedesis 10 What is a NET How are neutrophil stimulated to produce a NET 11 Now the pathway to produced prostaglandins and leukotrienes 12 What was the issue with Vioxx behind its removal from market 13 How do NSAIDs work Know the different cyclooxygenases What is a major drawback of COX 1 inhibition 14 What role doe Sialyl Lewis X play in margination 15 What are chemokines 16 What are DAMPS Example 17 What is the precursor for eicosanoid synthesis 18 What are acute phase proteins 19 Know the roles of the following IL 8 IL 6 TLR NF kB C reactive peptide C5a LTB4 C3b C3a IL 10 Monocyte CSF 20 Know the beneficial effects as well has harmful effects of inflammation Wound Healing 21 What are the three phases of wound healing 22 Be familiar with the process wound contraction and how fibroblast myofibroblast and TGF beta play a role 23 What is angiogenesis a What stimulates angiogenesis and why is it needed during inflammation and wound healing 24 What is granulation tissue a What is it made up of 25 Be familiar with the activation and secretions of fibroblast a Which is stronger Type



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