BME 120/220 Quantitative Physiology: Sensory Motor Systems, Fall 2017 Catalog Description: A quantitative and systems approach to understanding physiological systems. Systems covered include the nervous and musculoskeletal systems. (Design Units: 2) Prerequisites: BME 50B, BME 60C, Math 3A and Math 3D; or equivalent coursework in cellular/molecular biology, computer-aided design, linear algebra, and differential equations. Instructor: Beth Lopour ([email protected]) Office Hours: TBD Teaching Assistants: Hamsa Gowda ([email protected]) and Jessica Hsieh ([email protected]) Office Hours: Tues 10am-noon EH 2111 (Jessica); TBD (Hamsa) Schedule: Lecture: Monday, Wednesday, Friday, 3:00-3:50 PM, in DBH 1100 Discussion: Mon 7-8:20, Tues 7-8:20, Wed 5:30-6:50, 7-8:20 Textbook: Joseph J. Feher, Quantitative Human Physiology: An Introduction, 1st edition (2012). ISBN: 9780123821638 This is available as an E-Book through the UCI Libraries (Click here and then on “Connect to EBL. Restricted to UCI.”) Specifically, this course covers sections 3.1-3.3 (Neuron), 3.4-3.7 (Muscle), 4.1-4.4 (Neuron, Motor Control), 4.5 (Hearing, Motor Control), and 4.7 (Hearing). Course Website: EEE + Canvas Course Overview: This course is part of a two-course sequence in which students will apply concepts from engineering and mathematical modeling to understand the functional anatomy and physiology of human organ systems. Students will also learn to design (at a conceptual level) devices for restoring and enhancing human function. This course covers the nervous and musculoskeletal systems; the second course in the sequence, BME 121/221, covers the cardiovascular and pulmonary systems. ABET Course Objectives: 1. Students can apply knowledge of science to problems in Biomedical Engineering. 2. Students can access resources to solve open-ended biomedical problems.Attendance: Attendance at lectures is recommended, but not required. Attendance will be taken at all discussion sessions, and participation will be assessed through self and peer evaluation. Refer to the PBL section for more details. Grading Breakdown: For both BME 120 and BME 220 the breakdown is the same: 24% Midterm 32% Cumulative Final 16% Problem-Based Learning: Written report 16% Problem-Based Learning: Video or Research proposal 12% Open-book quizzes (3 x 4%) Grade Disputes: Any errors in grading must be reported within one week of when the assignment was returned. There is a “double or nothing” policy for regrades: you will either receive full credit for the disputed question or you will receive no points at all. Late Work Policy: PBL deliverables are generally due at the end of each session, except as indicated on the PBL information sheet. No late PBL assignments will be accepted. Makeup exams must be requested in advance with valid excuse and will consist of an oral exam at a time and place determined by the student and professor. E-mail Policy: Both the instructor and TAs will aim to respond to e-mails within 24 hours. If you send an e-mail the afternoon or evening before an assignment is due, you may not get a response until the next day. Please read this syllabus in full before sending the e-mail – the answer to your question may be here! Academic Honesty Policy: Academic honesty will be strictly enforced. Students found cheating, plagiarizing, or otherwise committing dishonest academic conduct will receive a zero on the assignment or exam and a written report will be filed for their permanent student record. Multiple or severe acts of academic dishonesty may result in a failing grade for the course. If you are unsure what constitutes plagiarism, please read What is Plagiarism? from the Yale Center for Teaching and Learning. The UCI Academic Senate Policy on Academic Honesty is also a good source of information.Detailed course Schedule: Week Date Topic What’s Due 0 9/29 Course Introduction 1 10/2 (M) Neuron 1 10/2-10/4 PBL – Identify unknowns List of questions 10/4 (W) Neuron 2 10/6 (F) Neuron 3 2 10/9 (M) Neuron 4 10/9-10/11 PBL – Review literature List of references; make writing plan 10/11 (W) Neuron 5 10/13 (F) Neuron 6 3 10/16 (M) Neuron 7 10/16-10/18 TA discussion section (Neuron discussion) 10/18 (W) Hearing 1 10/20 (F) Hearing 2 Quiz 1 – Neuron (Th 3pm-Fri 3pm) 4 10/23 (M) Hearing 3 10/23-10/25 PBL – Physical Design Written report due; Criteria/Constraints and Decision matrix 10/25 (W) Hearing 4 10/27 (F) Hearing 5 5 10/30 (M) Hearing 6 10/30-11/1 TA discussion section (Hearing discussion & midterm review) 11/1 (W) Hearing 7 11/3 (F) Muscle 1 Quiz 2 – Hearing (Th 3pm-Fri 3pm) 6 11/6 (M) Muscle 2 11/6-11/8 PBL - Algorithm Block diagram 11/8 (W) Midterm Review 11/10 (F) No Class – Veteran’s Day 7 11/13 (M) Midterm 11/13-11/15 PBL – Script/Outline 11/15 (W) Muscle 3 11/17 (F) Muscle 4 8 11/20 (M) Muscle 5 11/20-11/22 TA discussion section (Muscle discussion on Monday & Tuesday) Video script or proposal outline due 11/22 (W) Motor Control 1 Quiz 3 – Muscle (Tues 3pm – Wed 3pm) 11/24 (F) No Class – Thanksgiving 9 11/27 (M) Motor Control 2 11/27-11/29 PBL presentations Videos/Proposals due (submitted online) 11/29 (W) Motor Control 312/1 (F) Motor Control 4 10 12/4 (M) Motor Control 5 12/4-12/6 TA discussion section (Motor Control discussion/Final exam review) 12/6 (W) Motor Control 6 12/8 (F) Final Review Finals Mon 12/11 Final Exam, 4-6pm Problem-Based Learning (PBL) Project Introduction: The PBL assignment is an open-ended conceptual design project intended to foster learning in student-led small groups. There will be one PBL project spanning seven 80-minute sessions (see chart below), and teams will consist of 4-5 students. Just as in real-world engineering, there is no “correct” solution to the design problem. It is meant to be challenging, but also rewarding! Although the goal is for your group to work through the project independently, do not hesitate to ask for guidance or clarification from the TAs and instructor. Our job is to facilitate your learning. Week Date Tasks Deliverable 1 10/2-10/4 Identify Unknowns - Ice breaker, divide into groups of 4-5 *** TA’s introduce topic of design problem *** - Identify unknowns List of questions that your group will need to answer about the topic 2 10/9-10/11 Find Resources - Identify relevant references - Create a writing plan for your group List of references (min. of 1 per