CU-Boulder PSYC 2841 - Unit 4 Course Packet Key (9 pages)

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Unit 4 Course Packet Key



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Unit 4 Course Packet Key

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Pages:
9
School:
University of Colorado at Boulder
Course:
Psyc 2841 - Independent Study (Lower Division)

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MCDB 2150 Principles of Genetics Course Packet Fall 2017 Unit 4 Applications of Genetics Class 31 Gene Interactions Complementation and Epistasis 1 Three true breeding mutants with the same disease phenotype were isolated When crossed mutants 1 and 2 showed complementation and mutations 1 and 3 showed non complementation A Fill in the pedigrees below to reflect this information B Using capital and small letters to represent different alleles write the genotype of each individual in the blank beside the symbol You can choose which letter s to use C If the female and male from generation 2 of the two pedigrees above were to have offspring what percent of their offspring would show the mutant phenotype AaBb X aaBB 50 2 You are studying the genetics of eye formation in fruit fly 5 different mutant strains of fly have been isolated A E and each shows a recessive eye absent trait i e very small or no eye Crosses were performed as follows to test complementation and produced progeny with wild type eyes or eye absent A B C D E A B C D E A Based on the information in the table at least how many genes are needed to make an eye in fly 2 B Which flies have a mutation in the same gene are in the same complementation group ABE DC MCDB 2150 Principles of Genetics Course Packet Fall 2017 3 Autosomal recessive mutations in two different genes cause worms to produce defective eggs One mutant ee lays mis shapen eggs The other mutant qq lays dead eggs You cross together a mutant worm that lays mis shapen eggs with a mutant that lays dead eggs The offspring of this cross all can lay normal eggs You cross the F1 progeny with each other and find 27 worms that lay normal eggs 8 that lay mis shapen eggs and 15 that lay dead eggs A What is the ratio of phenotypes What inheritance pattern does this ratio suggest What can you conclude about the interaction between the two gene products 9 normal eggs 4 dead eggs 3 mis shapen eggs recessive epistasis Q is epistatic to E B What are the genotypes of the F2 progeny 27 normal eggs E Q 8 mis shapen eggs eeQ 15 dead eggs E qq and eeqq Class 32 Developmental Genetics I Maternal and Cytoplasmic Inheritance 1 Fill in generations 2 and 3 on two pedigrees below so that they are consistent with their modes of inheritance Use a if you are unsure of the phenotype The female in the third generation would not be colored in because her mom has to be Aa The son in generation 3 is because we do not know his mother s genotype MCDB 2150 Principles of Genetics Course Packet Fall 2017 2 In worms protein A activates Protein B Protein B when active inhibits apoptosis Protein A is inactivated by phosphorylation A Draw the pathway for apoptosis involving proteins A and



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