Wright BIO 2110 - BIO2110_f2016_exam3 (14 pages)

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BIO2110_f2016_exam3



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BIO2110_f2016_exam3

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14
School:
Wright State University
Course:
Bio 2110 - Principles of Molecular and Classical Genetics

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Name BIO 2110 Genetics Exam 3 9 December 2016 See last page for potentially useless formulae Show your work for all problems calculators permitted 1 Variation in body color pattern in newts results from allelic variation at a single gene Dominance relationships among these alleles are shown below Also shown is the distribution of phenotypes within a population of newts From these data determine the frequencies of all alleles and genotypes for this gene Assume this population is in Hardy Weinberg Equilibrium genotype AA Aa A phenotype phenotypic distribution Green with yellow stripes 228 aa Green with large yellow spots 300 a Green with small yellow spots 480 Green no yellow spots 192 2 Saltwater crocodile populations currently are present in the Irrawaddy Delta in Myanmar and in northern Australia Adults in both of these populations grow to a length of 23 feet F1 hybrids from crosses between these populations also grow to a length of 23 feet Among 768 F2 adults three were observed that were 35 feet long i Describe a quantitative genetic model to explain the presence of these 35 footlong crocodiles in the F2 population i e What were the genotypes of the P0s in this hybrid cross ii Based on your model what would be the smallest F2 crocodile observed 3 Fang length variation in Smilodon fatalis resulted from allelic variation at a single gene Dominance relationships for this gene are shown below Also shown are the relative fitnesses of genotypes and the initial frequencies of alleles for this gene Determine allelic and genotypic frequencies for this gene through two generations of selection Assume no other departures from Hardy Weinberg Equilibrium genotype AA Aa aa fang length 8 inches 9 inches 1 inch relative fitness 0 7 1 0 0 2 allele A a initial frequency p 0 9 q 0 1 4 Size variation in Pterois sphex is normally distributed see below How would this distribution change if predation selectively targeted i ii iii iv smaller fish smaller and larger fish average sized fish What is each of these types of selection called Show your answers graphically i e below the distribution show draw near distributions that would result from the described selective regimes 5 Ostrich height is a quantitative trait Shown below are cumulative distributions for the sizes of backcross progeny that are homozygous or heterozygous at the DM 3 marker Based on these distributions i what is the probability p value that the distribution of homozygotes is equal to the distribution of heterozygotes Round D statistic off to the nearest value found in Table 2 ii what is the Lod score for DM 3 Table 1 Cumulative Distributions for DM 3 homozygotes and heterozygotes Height 8 9 10 11 12 13 14 15 16 17 18 19 20 Homozygotes 0 071 0 071 0 214 0 286 0 357 0 500 0 714 0 857 0 929 1 000 1 000 1 000 1 000 Table 2 p values for K S



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