Wright BIO 2110 - Rec4_splicing and mRNA export (2 pages)

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Rec4_splicing and mRNA export



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Rec4_splicing and mRNA export

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2
School:
Wright State University
Course:
Bio 2110 - Principles of Molecular and Classical Genetics

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BIO 2110 Genetics Recitation 4 Splicing and mRNA export Group Members Name 1 Below are shown i An RNA pol II transcript that includes two exons and one intron Selected sequences in this transcript are shown ii Two snRNPs Shaded shapes in these diagrams represent the protein components of the snRNPs Lines represent the RNA components of the snRNPs Selected sequences in the snRNAs are shown Indicate where each of the snRNPs would bind to the pol II transcript Explain why these snRNPs would bind at these specific locations on the transcript Draw the on the transcript the molecular interactions that would result these snRNPs binding at these sites snRNP A snRNP B BIO 2110 Genetics Recitation 4 Splicing and mRNA export Group Members Name 2 How does the binding of snRNPs to an intron facilitate splicing What is the role of the branch point adenosine in splicing 3 Genes that don t have introns are poorly expressed have low mRNA abundance in the cytoplasm Insertion of introns into such genes improves their expression mRNA abundance in the cytoplasm increases Provide an explanation for this observation based on what you know about the transcription processing and or mRNA export of protein coding genes



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