U-M STATS 545 - Brief Review of Biological Concepts (2 pages)

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Brief Review of Biological Concepts



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Brief Review of Biological Concepts

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Pages:
2
School:
University of Michigan
Course:
Stats 545 - Mol Gen&Epigen Data
Mol Gen&Epigen Data Documents

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Brief Review of Biological Concepts 1 Biological molecules Small molecules macromolecules Physical properties size charge hydrophobicity hydrophilicity flexibility Structural properties conformation binding sites Molecular recognition Biological polymers DNA Nucleic acids in DNA RNA Nucleic acids in RNA Complementary base pairs hybridization double stranded structure of DNA Protein Amino acids Orientation of biological polymers 30 50 Amino carboxyl Conformation of polymers 2 Information coding and flow Central dogma DNA RNA protein Transcription RNA polymerase Transcription factor Translation Ribosome Transfer RNA Codon universal genetic code punctuation codons Structure of the genome Nuclear and mitochondrial genomes Chromosomes Genes introns exons Regulatory sites Chromatin structure Other telomeres centromeres etc 1 Heredity Germ cell somatic cell Diploid haploid Meiosis Mutation Natural selection evolution genetic drift 3 Structure and function of proteins Primary secondary tertiary Conformation fold Post translational modification Enzymes Cell structure Signaling Protein and protein RNA complexes Protein breakdown 4 Regulation of gene expression Control of transcription rate mRNA degradation in the nucleus Control at the nuclear membrane mRNA degradation in the cytoplasm Control mechanisms at the ribosome mRNA processing splice variants 5 Cells Prokaryotes eukaryotes archaea Cellular substructure membranes compartments nucleus mitochondria Metabolism Growth Transport Cell cycle Cells in a multicellular organism Differentiation Stem cells Housekeeping genes 2



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