LS3 Section 1, Winter 2014 1 of 3 Course Information LS3 Section 1: Introduction to Molecular Biology Instructors: Fang Wang, Ph.D. [email protected] Office Hours: Monday 11:15-12:15 pm, Hershey Hall 318 Friday 11:15-12:15pm, Hershey Hall 318 Course Website: https://ccle.ucla.edu/course/view/14W-LIFESCI3-1 Text: Molecular Biology: Principles and Practice Course TAs: Shannon Beaty [email protected] Ellice Kang [email protected] Lauren Neves [email protected] Yi Ying [email protected] If you have questions related to the discussion sections please ask the appropriate TA. Lectures: MWF 10- 10:50 am La Kretz 110 Lectures will be based on the reading listed in this handout. There will be additional examples given in the class that may not be from the text, but are chosen to help in understanding different concepts in the course. Lectures will be posted on the course website the night before by 9PM so that you can print them out and bring them to class if you choose. iClickers: Students are required to bring iclickers to class to respond to questions posed during lecture. You can use i>clicker +, i>clicker2, or i>clicker GO for the course. You must register your clicker on the CCLE course webpage to be included in the course roster and to receive participation points. You must answer all of the questions each day to receive full participation credit for that day. Participation during the first week of lectures will not be counted towards your points, to allow you time to buy/register the clicker. Points will be counted beginning week 2. Each lecture thereafter is worth one point. Each student can miss three lectures and not be penalized. Lecture participation is worth about 20 points towards your final grade. You may not share a clicker with someone else in this lecture. Answering questions for another student not in attendance constitutes cheating and both students involved will be referred to the Dean of Students for academic dishonesty. You should check your participation daily to make sure that you are receiving points. If you have noticed a problem (i.e. your points aren’t showing up and you know you attended class) then you must notify your professor immediately. Many times the issue will be that you did not register your clicker correctly. I am not responsible for any issues with your participation grade if you fail to inform me of any problems during the quarter and choose to wait until the end of the quarter to bring up any issues. If you lose your clicker and purchase another one you must register your new clicker on the CCLE course webpage. https://www.coursehero.com/file/9344116/LS3-1-Winter-2014-Syllabus/This study resource wasshared via CourseHero.comLS3 Section 1, Winter 2014 2 of 3 Discussion sections: These discussion sections are approximately 75 minutes in duration and attendance is mandatory. Discussion sections are run by your TA’s and are your opportunity to ask questions about material that may seem unclear, or to go over worksheets that have been assigned to help you study for the exams. There will be group exercises given during discussion sections. You must attend the discussion section in which you are enrolled. If under extenuating circumstances you need to switch a section you must confirm it with your TA and the TA for the section you will be attending. You may not simply show up to another section without arranging everything ahead of time. The discussion sections are worth 30 points (3 points per session) towards your final grade. Exams: You have two midterms and one final for the course. Both midterms are held in the evenings, so please plan accordingly. The midterms for this class are on Tuesday, January 28, 5pm – 6:50pm and Tuesday, February 18, 5pm – 6:50pm. The final exam (cumulative) will be held on Thursday, March 20, 11:30am – 2:30pm. Material for the exams will be taken from lectures, the text, additional posted readings, problems and material from your discussion sections. You will have a chance to review your exam, but you will not be able to keep your midterms or finals. Regrading policy: Any request for a regrade must be made in writing within one week of the exam being reviewed by you. If you think there has been an error during the grading of your exam then write a note explaining the error and page number, attach this to the front of the exam, and return to your TA during discussion. Please note that when exams are regraded, the entire exam is reevaluated to look for errors. Administrative issues: All questions related to administrative issues should be taken to the Life Sciences Core Education Office Hershey Hall, Room 222 (310) 825-6614 For enrollment questions, you may contact this office listed above by email [email protected]. If you miss class and have documentation for your absence, you may contact Michelle Veintimilla at [email protected] in the Life Sciences Core Education Office. Documentation must be submitted within 7 days of the absence. Points Breakdown: Midterm 1 100 Midterm 2 100 Final Exam 200 Discussion 30 Participation (iclickers) 20 Total Points 450 You should keep track of your own points so that at any time during the quarter you know your standing. If for any reason you have concerns about your points, then that is a great time to come and see your professor so we can discuss study techniques or alternative strategies to help you along in this course. https://www.coursehero.com/file/9344116/LS3-1-Winter-2014-Syllabus/This study resource wasshared via CourseHero.comLS3 Section 1, Winter 2014 3 of 3 Lecture Schedule and Readings: Week Topics Reading 1 Introduction, discovery of genetic material Protein structure Protein function Chapter 2 Chapter 4 Chapter 5 2 DNA and RNA structure DNA topology Chromosome structure Chapter 6 Chapter 9 Chapter 10 (10.1 and 10.2) 3 DNA replication Chapter 11 4 (Midterm I) DNA mutation and repair Techniques of molecular biology–I Chapter 12 Chapter 7 (partial) 5 Transcription RNA processing Chapter 15 Chapter 16, 6 The genetic code Translation Chapter 17 Chapter 18 7 (Midterm II) Genome, transcriptomes, and proteomes Techniques of molecular biology–II Chapter 8 Chapter 7 (partial) 8 Regulating the flow of information Regulation of gene expression in Bacteria Chapter 19 Chapter 20 9 Transcriptional and post-transcriptional regulation of gene expression in