PowerPoint PresentationSlide 2Slide 3Slide 4Slide 5Slide 6Slide 7Slide 8Slide 9Slide 10Slide 11Slide 12Slide 13Slide 14Slide 15Slide 16Mitosis plays a role in:Slide 18Slide 19Homework #3 is due 11/19Bonus #2 is postedhttp://www.freshminds.com/animation/alan_watts_theater.htmlDo telomere dynamics link lifestyleand lifespan?Pat Monaghan and Mark F. HaussmannTRENDS in Ecology and EvolutionVol 21 pg 47Telomere length varies in different parts of adults:telomeres - mitosisstomach &blood cells....short - oftenmuscle &brain……….long - rareliver &kidney……..short - raregametes……longTelomeres are non-gene DNA at the ends of DNA strands.Telomeres are more sensitive DNA damage, and may act as a sensor for overall DNA damage level in a cell.Does telomere length indicate longevity?Zebra finchTelomere length in red blood cells of different birdsFig. 1 TRENDS in Ecology and Evolution Vol 21 pg 47Age (years)common ternTelomere length in red blood cells of different birdsFig. 1 TRENDS in Ecology and Evolution Vol 21 pg 47Age (years)albatrossTRENDS in Ecology and Evolution Vol 21 pg 47Telomere length in red blood cells of different birdsLeach’s storm petrelTelomere length in red blood cells of different birdsFig. 1 TRENDS in Ecology and Evolution Vol 21 pg 47Zebra finchLeach’s storm petrelcommon ternalbatrossTelomere length in red blood cells of different birds, different species have different patterns of telomere length and ageFig. 1 TRENDS in Ecology and Evolution Vol 21 pg 47Fig. 2 TRENDS in Ecology and Evolution Vol 21 pg 47Telomere length in white blood cells of different aged people. Telomere length generally declines, but there is wide variabilityTHE LANCET • Vol 361 • pg 393Telomere length and mortality in people over 60 years oldupper 50% of telomere lengthlower 50% of telomere lengthproportion surviving %years after initial assessmentTelomere length may indicate biological age.Early stress may cause premature telomere degradation.For life to exist, the information (genes) must be passed on.{Mitosis:producing more cells}{Meiosis:producing gametes}The Cell CycleFig 2.9Mitosis:A DNAPerspectiveMitosis plays a role in:•Growth and Development•Repair and Turnover of Cells•Reproduction–AsexualstartofmitosisFig 2.10TheMitoticSpindle(micro-tubules)SisterChromatidsA basic look at