Student Microbiome Presentations (2)!!Lactobascillicus?!Where and how? Bacillus difficile by Hall and O'Toole in 1935 as part of a normal flora of newborn infants!diarrhea, fever, nausea abdominal cramping, dehydration,!500,000 cases per year, 29,000 deaths per year, 17th leading cause of death in ppl 65 yrs and older in 2011!overuse of antibiotics in 1970 led to the rise of bacillus difficile!People feel depressed about this disease/ embarrassed: stigmatized, they have to be isolated within the hospital!Who it more susceptible? hospital patients, people n nursing homes!An aerobic bateria!resistent to alcoholic sanitizers!!Candida albicans!a species of fungus, often grows as a yeast (can give rise to yeast infections)!it is polyphenic: it can take on different forms depending on which environment that its in!fun fact: one of the few exceptions codon CUG codes for leucine!Epidemiology: accounts for 44.4% of infection in human populations!Mortality rates are 30-50% (quite low) however only because the patients that have it are immunocompromised. !Treatment: anti fungal medication prescribed by a doctor, probiotics may help as well. very serious infection stay require IV !!Gut bacteria, nutrition, and obesity!obesity: having a BMI of 30 or higher!metabolic syndrome: 3 out of the following to be diagnosed:!-obesity!-diabetes!-highbloodpressure!-excess body fat!~25% adult in us have it!There is a difference in gut bacteria of obese people and lean people!gut microbiota play the following roles : digestion !changing from a diet low in fat and sugar to high in fat and sugar can change guy microbiota in one day!metabolic syndrome: TLR-5 receptor mutation increases chances of getting metabolic syndrome (not a good idea to increase fiber in diet because it can ferment!)!Artificial sweeteners: bad! saccharin kills of gut bacteria and bad bacteria feed off of saccharin (not proven, but very possible)!Adipose tissue and bowling: brown uses energy to create body heat, white stores excess energy as fat. Aging and weight gain associated with lower levels of BAT!! !Your brain on Bugs !gut bacteria and mental health!intestinal bacteria make up 2% of human body mass!can be determined by genetic factors and environmental factors!the help produce vitamins and amino acids, break down food!microbiota are responsible for the production for some neurotransmitters!mental illness and gut flora are lined to anxiety, depression, schizophrenia, and
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