PROBLEM SET 8 MCB2210 Spring 2015 86 Which of the following is not an example of a microtubule organizing center MTOC a centrosome These three all contribute to the b flagella basal body MTOC Flagella and Cilia basal c cilia basal body bodies act as templates for for d centromere centrioles and the MTs that grow e all of the above off of them to form the MTOC 87 All of the following are true about centrioles except MTs arise from a they are the nucleating site for spindle microtubules Cytoplasmic cilia gamma turc within b they are self replicating Thru the basal body such as primary the pericentriole c cytoplasmic microtubules do not directly radiate from the ends of centrioles cilia radiate from material of the d they usually come in perpendicular pairs basal bodies centrosome e they are found within animal cell centrosomes 88 Which of the following is a function of a cilium a moving a cell from place to place b moving fluid and particulate material past a cell c a role in sensory function in monitoring the properties of extracellular material d moving vesicles to the cell body e all of the above 89 Which of the following is a difference between cilia and flagella a Flagella are usually longer than cilia b Cilia can be more numerous on the cell surface than flagella c Cilia utilize kinesin to move while flagella use dynein Both cilia and flagella use d Cilia never move but flagella do kinesin and dynein to move e a and b motile 90 Which of the following are differences between cilia flagella and basal bodies centrioles Note primary cilia a Basal bodies centrioles have 9 triplet microtubules on the periphery while lack the 2 central MTs cilia flagellae have 9 doublets b Basal bodies centrioles have 9 doublet microtubules on the periphery while cilia flagellae have triplets c Basal bodies centrioles have no central microtubules cilia flagellae have 2 single central microtubules d Basal bodies centrioles have no central microtubules cilia flagellae have 3 single central microtubules e a and c 91 Which component of the centrosome is responsible for nucleating cytoplasmic microtubules in vivo a The basal body b The centriole c The nucleus d TURC 17 e The axoneme 92 In an electron micrograph an object is visible in cross section It appears to be made of nine sets of three hollow tubes that are fused together They are arranged in a pattern that looks much like a pinwheel Next to this object is a similar object oriented perpendicularly to it What is the object in the micrograph a A microtubule Centriole basal body b A centriole c A spindle d A flagellum e A cilium 93 Which of the following sites within a cell are places where microtubules are found a mitotic spindle b cilium Material between the nuclear c nucleoplasm d a and b membrane and the nucleus e a b and c 94 The structure that contains two barrel shaped centrioles surrounded by amorphous electron dense pericentriolar material is called a n a centrosome b nucleus c pericentriosome d spindle e aster 95 What word below describes the arrangement of microtubules in a centriole a doublet Basal body centriole does not have any central MTs b triplet c 9 0 d perpendicular e b and c 96 The outer microtubules in a motile cilium are generated directly from microtubules in a n a centromere b gamma TURC c basal body d PCM e flagellum 97 The outer microtubules in a primary cilium are generated directly from microtubules in a n a centriole basal body b PCM pericentriole material c centromere d gamma TURC 18 e flagellum 98 Which of the following organelles are essentially equal in structure to basal bodies a centrioles b microfilaments c gamma TURC d centromeres e centrosomes 99 Which of the following microtubules are the most stable polymers a spindle microtubules b cytoplasmic microtubules c microtubules undergoing catastrophe d microtubules of cilia MTs of Cilia don t shrink and grow as often as spindle and cytoplasmic MTs e a and b 100 What is another name for motile organelles projecting from some eukaryotic cell surfaces a cilia b collagen fibrils c flagellae d a and c e projectosomes 101 The core of a cilium is called the a flagella b filament c cilioneme d axoneme e flagellosome 102 Which of the following would be evidence that all living eukaryotes have evolved from a common ancestor a No matter where cilia are seen they are the same length b Cilia always contain microfilaments c Cilia are short in all locations where they are found d The 9 2 pattern of axonemes is seen in a variety of organisms from protists to mammals e All microtubules in axonemes are oriented in the same direction 103 Cell movement plays an important role in which of the following processes that can take place in mammals a Inflammation b Wound healing c Metastasis spread of cancer d Embryonic development e All of the above 104 Chemotaxis can be defined as a process of 19 a chemokine production b directed cell movement toward a signal c activated phagocytosis d cytokine release e blood clot formation 105 What change in the cells of the blood vessel endothelium causes the increase in adhesion Endothelial cells of neutrophils to the surfaces of the endothelial cells in the region of the injury display selectin a secretion of a chemoattractant to attract the neutrophils b display of selectins on the surface of the activated endothelial cells in the damaged area receptors when c temporary display of integrins on the surfaces of the activated endothelial cells in the Leukocytes such as damaged area neutrophils are d formation of gap junctions between the neutrophil and the endothelial cells needed e no change the change actually occurs on the neutrophil only 106 What change in the neutrophil is likely to allow it to stick tightly to the endothelium to stop rolling a Secretion of an extracellular glue b display of selectins on its surface c Activation of integrin binding by phosphorylation of the cytoplasmic domain d Activation of integrin binding by phosphorylation of the extracellular domain e no change the change actually occurs on the endothelium only 107 Which of the following correctly describes the sequence of adhesive changes between a leukocyte and the endothelium during inflammation a Strong adhesions form first mediated by selectins on leukocytes followed by weak adhesions mediated by integrins on endothelial cells b Weak adhesions form first mediated by integrins on endothelial cells followed by strong adhesions mediated by integrins on leukocytes c Strong