DOC PREVIEW
SC CHEM 334 - Continued synthesis of amines

This preview shows page 1 out of 3 pages.

Save
View full document
View full document
Premium Document
Do you want full access? Go Premium and unlock all 3 pages.
Access to all documents
Download any document
Ad free experience
Premium Document
Do you want full access? Go Premium and unlock all 3 pages.
Access to all documents
Download any document
Ad free experience

Unformatted text preview:

Chem 334 1nd Edition Lecture 24Outline of Last Lecture I. Acidity and synthesis of aminesOutline of Current Lecture II. Alkylation of AminesIII. Arendiazonium Salt ReactionsCurrent LectureAlkylation of amines:Primary, secondary, and tertiary amines can do SN2 reactions with alkyl halides. Br NH3 NH3 Br-The problem with this is that we end up with a mixture of products from these reactions. To avoid this problem, we use over alkylation as well as some elimination.Alkyl groups are electron donating. Therefore the product formed from these reactions is typically a good nucleophile. We can get a single product from the reaction if we use the amine in excess. Br NH2(excess) NH Arendiazonium Salt reactions: N≡NArendiazonium salts can be synthesized from primary aryl amines using Sodium nitriteThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.NH2 NaNO2 N≡N 2 equiv. HClDiazonioms can be replaced by many different functional groups;N2 H3O/Δ HON2 H3PO2 Sandmeyer Reactions:N2 CuCl ClN2 CuBr BrN2 CuCN CNIodination:N2 KI IFluorination:N2 HBF4


View Full Document

SC CHEM 334 - Continued synthesis of amines

Download Continued synthesis of amines
Our administrator received your request to download this document. We will send you the file to your email shortly.
Loading Unlocking...
Login

Join to view Continued synthesis of amines and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view Continued synthesis of amines 2 2 and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?