BIOM 121 1nd Edition Lecture 23 Outline of Last Lecture I. DNAa. Research Methodsb. Structurec. ReplicationOutline of Current Lecture II. DNA Replication TerminologyCurrent LectureDNA Replication Terminology- Topoisomerase: helps relieve the strain on the DNA ahead of the replication fork by breaking, swiveling, and rejoining DNA strands.- Helicase: enzymes that untwist the double helix at the replication forks, separating the two parental strands.- Primase: synthesizes RNA primers, using the parental DNA as a template.- Single-strand binding proteins: bind to unpaired DNA strands and keep them from re-pairing.- RNA Primer: Complementary strand that is created by primase.- Leading Strand: the new complementary DNA strand synthesized continuously along the template strand towards the replication fork.- Lagging Strand: discontinuously synthesized DNA strand that elongates by means of Okazaki fragments away from the replication fork.- DNA Polymerase: catalyze the synthesis of new DNA by adding nucleotides to a preexisting chain.- Okazaki Fragments: a short segment of DNA synthesized away from the replication fork on a template strand.- DNA Ligase: a linking enzyme essential for DNA replication that catalyzes the covalent bonding between Okazaki fragments.These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a
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