ANSC 303 1st Edition Lecture 25Outline of Last Lecture I. Fatty Acid SaturationII. Fatty Acid IsomersA. Geometrical isomers B. Chain branchingIII. Physical TraitsIV. Fatty Acid NomenclatureV. Omega SystemVI. Essential FAVII. TriglyceridesOutline of Current Lecture I. Lipid DigestionA. Monogastric DigestionB. Digestion of LipidsC. Specificity of LipasesD. Lipid Digestiona. Phase 1 - emulsification b. Phase 2 - enzymatic digestion E. BileF. Absorption - Micelle FormationCurrent LectureI. Lipid DigestionA. Monogastric Digestiona. Triglycerides (TG) are too lareg for absorptionb. Lipids are polarc. In the small intestine:i. Emulsification - TG mix with bileii. Digestion - TG mix with pancreatic secretionsB. Digestion of Lipidsa. May begin in the mouth/stomachThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.i. Usually nursing animalsii. Does not require bileiii. Lingual lipase - monogastriciv. Pregastric lipase (esterase) - ruminant (nursing)v. Gastric lipase - monogastricb. Undigested lipids do not let the stomach empty out c. This leads to satiey C. Specificity of Lipasesa. Lingual, pregastric, and gastric lipasei. Highly stable (need low pH)ii. Do not require bile saltsiii. Prefer to act on:A. TG with short or medium chainsB. FA at sn-3 positioniv. Benefits the infantb. Most TG occur in the small intestineD. Lipid Digestiona. Phase 1 - emulsification i. Overcomes the TG solubility issuesii. Needs bileiii. Produced by liver, stored in gallbladderiv. Increases SAb. Phase 2 - enzymatic digestion i. Overcomes the large sizeii. Needs pancreatic colipaseiii. Interacts with TG and pancreatic lipaseA. Activated by trypsin B. Displaces bile C. Above two important to pancreatic lipaseE. Bilea. Produced in liver, stored in gallbladderi. Not in the horseb. Alkaline solutioni. Bile saltsii. Cholesteroliii. Lecithiniv. Bilirubin c. Responsible for fat emulsification d. Increases surface areaF. Absorption - Micelle Formationa. Complex lipid materials soluble in waterb. Micelle contains bile salts, phospholipids, and cholesterol c. Combines with 2-monoglyceride, FFA's, and fat-soluble
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