ZOL 341 1st Edition Lecture 17 Outline of Last Lecture I F plasmids II F factor mating III Cotrans frequency IV Transduction V Generalized transduction Outline of Current Lecture II Electrophoresis III Restriction endonucleases IV RFLP V Molecular probes VI Heterozygote advantage Current Lecture gel electrophoresis smaller molecules migrate more rapidly than larger molecules SNP single nucleotide polymorphisms restriction endonuclease enzymes that cut DNA at specific sequences restriction sites are usually palindromes each strand of the ds restriction sequence has the same nucleotide order RFLPs restriction fragment length polymorphisms inherited variability in the number length of restriction fragments molecular probes antibodies or single stranded nucleic acids that specifically bind to target molecules heterozygote advantage causes populations to evolve a gene pool with high levels of both the normal and mutant alleles These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute the advantage of the heterozygosity is balanced by the disadvantages associated with homozygosity for either allele equilibrium frequency the gain and loss of the mutant alleles is equal
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