DOC PREVIEW
UT Knoxville BIOL 240 - DNA Replication
Type Lecture Note
Pages 2

This preview shows page 1 out of 2 pages.

Save
View full document
View full document
Premium Document
Do you want full access? Go Premium and unlock all 2 pages.
Access to all documents
Download any document
Ad free experience
Premium Document
Do you want full access? Go Premium and unlock all 2 pages.
Access to all documents
Download any document
Ad free experience

Unformatted text preview:

BIOL 240 1st Edition Lecture 18Outline of Last Lecture I. Griffith’s Transformation ExperimentII. Life Cycle of T-even BacteriophageIII. Chemical Components of DNA and RNAIV. DNA StructureOutline of Current Lecture I. Replication Overview1. Formation of replication fork2. synthesis of leading strand3. synthesis of lagging strandCurrent LectureI. Replication Overview1. Formation of replication fork—two stands of DNA separate and are used as templates for new strands- proteins work together unwinding the DNA; DNA helicases bind and separate strands, while others break bonds and prevent bonds from reforming - DNA polymerases build new strands of DNA- since the parental strands run in opposite directions, the new strands are made differently2. Synthesis of Leading Strand- built continuously and toward the origin of replication- DNA polymerase builds a new DNA strand by adding nucleotides one at a time (nucleotides must pair with their complementary nucleotide)3. Synthesis of Lagging Strand- built discontinuously in pieces- Okasaki fragmentsThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.- since this is built in fragments, each piece begins with a short RNA segment called an RNA primer by RNA polymerase. Then, a clamp surrounds the RNA primer and attaches to DNA polymerase and builds the rest of the fragment as DNA. Once complete, it is released from the polymerase.- once all the pieces are complete, there are still those RNA segments between the DNA segments. How are they replaced?- a different DNA polymerase removes the RNA and replaces it with DNA- DNA ligase is the cement that joins the pieces


View Full Document

UT Knoxville BIOL 240 - DNA Replication

Type: Lecture Note
Pages: 2
Download DNA Replication
Our administrator received your request to download this document. We will send you the file to your email shortly.
Loading Unlocking...
Login

Join to view DNA Replication and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view DNA Replication 2 2 and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?