MCDB 2150 1st Edition Lecture 18 Outline of Last Lecture I. Transcription & translation overviewOutline of Current Lecture II. Spontaneous mutationsa. Slippageb. Misalignmentc. Radiationd. Single nucleotide changesIII. Mutation typesa. Base substitutionb. FrameshifThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Mutation types: missense, silent or nonsense = base substitution frameshift = base insertion, deletion A point mutation that results in an amino acid is called a missense mutation A silent mutation is a point mutation that codes f or the same amino acid A nonsense mutation is a point mutation that changes an amino acid to a stop
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