ZOL 341 1st Edition Lecture 12 Outline of Last Lecture I Dosage compensation II Conclusions from Mendel III Allele interactions IV Codominance Outline of Current Lecture II Pleiotropy III Gene interaction IV Genetic dissection V Epistasis Current Lecture pleiotropy the alteration of multiple distinct traits by a mutation in a single gene gene interaction the collaboration of multiple genes in the production of a single phenotypic characteristic genetic dissection used to investigate gene action completion of one step generates the substrate for the next step in the pathway completion of every step is necessary to produce the end product epistasis the alleles of one gene modify or prevent expression of alleles of another gene mutation of one gene in a pathway may prevent the production of the end product a minimum of two genes are required these usually participate in the same pathway no interaction 9 3 3 1 ratio dominant suppression a dominant allele at one locus suppresses expression of a second locus genetic heterogeneity mutations in different genes can produce the same or very similar mutant phenotypes These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute genetic complementation when mating of two organisms with similar mutant phenotypes leads to wild type offspring complementation occurs when the mutations in the parents affect different genes
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