PSYC 304 1st Edition Lecture 8Outline of Last Lecture I. Brain Tour LinkII. The Brain’s Vital StatisticsIII. Brain AnatomyIV. Normal Age Related ChangesV. Models of the Aging Nervous System Outline of Current LectureI. Dementia (overview)II. Global Symptoms of DementiaIII. Diagnosis/Assessment – Need to Rule OutIV. Alzheimer’s DementiaV. Brain ChangesVI. Symptoms of Alzheimer’s DementiaCurrent LectureI. Dementia (overview)a. Loss of memory, judgmentb. Loss of mobilityc. Dependencyd. Progresses over timeThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.e. Behavior symptoms similar to other disorders (e.g. depression)II. Global Symptoms of Dementiaa. Disorientationb. Memory Problemsc. Coordination Problemsd. Mental Slowinge. Impaired Judgmentf. Personality ChangesIII. Diagnosis/Assessment – Need to Rule Outa. Depressionb. Drug Reactionsc. Metabolic Changesd. Nutritional Deficienciese. Head Injuryf. DehydrationIV. Alzheimer’s Dementiaa. 2x higher in femalesb. Approximately 5% over 65 yearsc. Approximately ½ of Nursing Home Residentsd. Public Health Problem ($100 billion a year)e. Estimates by 2050 (13.2 million vs. 4.2 million now)f. Death approximately 5-10 years after onsetg. Auguste D. – 1906 (age 51)i. One of the first cases of Alzheimer’s1. Had memory impairment, hallucinations& executive dysfunction2. Was confirmed only by autopsy after-the-fact.V. Brain Changesa. Brain shrinks in Alzheimer’sb. Senile Plaques & Tanglesi. Plaques start in neocortexii. Beta-amyloid Plaques1. Dense deposits of protein and cellular material that accumulate outside and around nerve cellsiii. Neurofibrillary Tangles1. Twisted fibers that build up inside the nerve cella. Ex. Deposits of Tau (a protein) accumulate inside of nerve celliv. Hippocampusv. Frontal & Temporal Areasc. 20% loss of neurons vs “normal”d. Changes can begin 10-20 years prior to Behavioral Symptomsi. Mild Cognitive Impairment Diagnosis (MCT)VI. Symptoms of Alzheimer’s Dementiaa. Usually appear > 60 yearsb. Gradual Memory Lossc. Decline in Ability to Perform Routine Tasksd. Disorientatione. Personality Changesf. Difficulty in Learningg. Loss of Language
View Full Document
Unlocking...