Biol 4610 1st EditionLecture 9Outline of Current Lecture 1. Biomembrane Structure2. Types of lipids in membraneCurrent LectureChapter 10 – Biomembrane structure- Define the cell- Separate inside from outside- Define organelles- Transporting- Signaling- Adhesion to other cells- Structure/interaction with cytoskeleton 10.1. Phospholipid Bilayers: Lipid Composition and Structural Organization3 types of lipids in most membranes:• Phosphoglycerides- stabilized by hydrophobic (vanderhaals) interactions and H bonds• Exoplasmic face: outside of cell• Cytoplasmic face: inside of cell• Phosphate group attached to Glycerol 3C and 2 fatty acyl chainsThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.Differing head groups on the phosphoglyceride Phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), and phosphatidylinostiol (PI)PC: most common head group (neutral at physiological pH)2) Sphingolipids – derived from sphingosine• 1 acyl chain is attached to glycerol by amide linkage• Makes the membrane thicker (because it’s longer relative to phosphoglyceride)3) Cholesterol – a 4-ringed hydrocarbon. • Also considered amphipathic • Used to add fluidity to membrane. If have all long chains, they pack together and are in arigid state. Cholesterol adds fluidity to
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