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UT Knoxville BIOL 240 - Inversion and Translocation
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BIOL 240 1st Edition Lecture 13Outline of Last Lecture I. Cystic FibrosisII. Single Nucleotide PolymorphismsIII. Chromosome RearrangementsOutline of Current Lecture I. Fragile X DiseaseII. InversionsIII. Robertsonian TranslocationCurrent LectureI. Fragile X Disease- Most common inherited mental disorder- Caused by mutations in the x-linked FMR1 gene- Fragile site near the tip of the X chromosomeII. Inversions- Change the order of the genes but no effect on gene balance- Paracentric—does not include the centromere- Pericentric—includes the centromere- Chromosome breakbroken ends joinrepetitive DNA segmentscrossover- Crossover suppressors (no crossing over within inverted region)These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.III. Robertsonian Translocation- Reciprocal translocation that fuses most of one chromosome with most of another- Most common between telocentric


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UT Knoxville BIOL 240 - Inversion and Translocation

Type: Lecture Note
Pages: 2
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