REHAB 205 1st Edition Lecture 6I. Multiple sclerosisa. Progressive inflammatory condition of the Central nerve system where myclin sheath surrounding the nerve cell fibers are deteriorating b. Scars the central nerve system with timec. “When the myelin deteriorates scar tissue will accumulate around the nerve fibers and interfere with the nerve impulses (Falvo, 2009).”II. Causea. Unknown for the most parti. Environmental and genetics can play a factorIII. Epidemiologya. Mostly in young adultsi. 20-40 years oldii. Mostly women (70%)b. 10 per 100,000 estimated have itc. 250,000-350,000 living in the united states estimated this conditiond. Asians and native Americans are examples of two ethnic groups that this condition is hardly ever seen in IV. Manifestationa. Relapsing-remittingThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.i. fluctuating course of exacerbates symptoms followed by little to no symptomsb. secondary progressive-i. cessation of fluctuations with slow deterioration c. secondary progressive with relapses-i. fluctuation with relapses and deterioration between relapsesd. primary progressivei. deterioration from beginning e. progressive relapsingi. progressive with relapsesV. Symptoms a. Numbnessb. Weaknessc. Dizzinessd. Spasticitye. Visual problemsf. Weaknessg. Poor/weak bowelVI. Treatmenta. No cureb. Relapse managementc. Medicine d. Lifelong diseasee. Not fatal in most casesf. Many need wheel chairsVII. Muscular Dystrophy a. Refers to a group of hereditary conditionsi. Weak musclesii. Muscle wastingiii. Progressively gets worseVIII. Formsa. Dychennei. Muscle wasting and weakness happens at rapid rateii. Detected within 7 years of lifeiii. Around 13 most need a wheel chairiv. Life span around 25 yearsv. Buildup of calcium in musclesb. Beckeri. Slower rateii. Detected around 25iii. Can walk into adulthoodiv. Condition will not lead to early deathIX. Cause for Beckera. Genetic deficiencies in body to create dystrophin and dystrophin proteinb. Without dystrophin, muscle tissue cannot regenerateX. Cause for Dystrophina. Each parent gives one chromosome i. Boys: X from mom, Y from dad = XY ii. Girls: X from mom, X from dad = XXiii. Gene is X linkedI. XX = girl• If baby girl inherits defective gene on X chromosome, she is a carrier• Other X chromosome suppresses it – no signs or symptoms of MD• XY = boy• If baby boy inherits defective gene on X chromosome, no suppression and willshow signs and symptoms of