Name__________________________________________ Section #_______________________________Biology 240, GeneticsQuiz – 5, week of Oct 27.Q 1. Which of the following statements is correct? a) Bacteria have one type of RNA, while the eukaryotes have three types.b) In bacteria all types of RNAs are transcribed by only type of RNA polymerase.c) In bacteria pre-mRNA is processed to produce mature mRNA.d) Both b and c are correct.Q 2. The final product of the ribosomal RNA gene is:a) Ribosomal proteins.b) Ribosomal proteins plus ribosomal RNA.c) Ribosomal RNA.d) rRNA:tRNA complex.Q 3. In bacteria, the sigma factor is____a) A part of the RNA polymerase core enzyme.b) Involved in transcription termination.c) The factor that transcribes RNA.d) A part of the RNA polymerase holoenzyme.Q 4. During transcription:a) Ribonucleoside triphosphates are used as substrates.b) Ribonucleoside monophosphates are used as substrates.c) Nascent RNA grows towards its 3’-end.d) Both a and c are correct.Q 5. In bacteria transcription is terminated by the:a) Formation of a hairpin structure in the nascent transcript.b) Formation of a hairpin on the template DNA strand.c) Dissociation of the sigma factor from the enzyme complex.d) Association of the sigma factor with nascent RNA.Q 6. The final product of every gene is:a) A polypeptide.b) An RNA.c) Involved in enzymatic reaction.d) None of the above.Q 7. Which of the following enzymes transcribes mRNA in eukaryotes?a) RNA polymerase I.b) RNA polymerase II.c) Both a and b.d) RNA polymerase III.Q 8. Intervening sequences are found in:a) Mature mRNA.b) Most bacterial genes.c) Between two genes on the same DNA.d) Pre-mRNAs.Name__________________________________________ Section #_______________________________Q 9. A gene has four introns. If the two DNA strands of this gene are allowed to anneal with the mature mRNA that this gene codes for,a) The exon sequences will form four loops.b) Four intron loops made of double-stranded DNA will form.c) Four loops made of RNA will form.d) Four loops made of DNA-RNA hybrid will form.Q 10. Polyadenylation is a process that adds adenylic acid residues at the:a) 3’-end of the mRNAs during transcription.b) 5’-end of the mRNAs during transcription.c) 3’-end of the mRNAs post-transcriptionally.d) 5’-end of the mRNAs post-transcriptionally.Q 11. Which of the following mechanisms happens post-transcriptionally?a) Splicing.b) Capping.c) Both a and b.d) Neither a not b.Q 12. Which part of the genes has the protein coding information?a) Exons.b) Introns.c) Leader sequence.d) Poly-A tail.Q 13. Spliceosomes are made of:a) Proteins only.b) snRNAs only.c) Snurps.d) Ribosomes.Q 14. Splicing is a process that:a) Joins introns and removes exons.b) Joins exons, removes introns and adds poly (A) tail.c) Adds cap and poly (A) tail.d) Joins exons and removes introns.Q 15. The conserved GU sequence is found at the______________a) 5’-end of the introns.b) 3’-end of the introns.c) Both ends of introns.d) Branch point sequence of the introns.Name__________________________________________ Section #_______________________________Q 16. Splicing involves:a) One transesterification reactions.b) Two transesterification reactions.c) Ligase reactions.d) RNA hydrolysis.Q 17. During splicing a lariat is formed due to the covalent linkage between the:a) 2’-OH group of branchpoint adenine and the 5’-guanine of the intron.b) 2’-OH group of the branchpoint adenine and the 3’-guanine of the intron.c) 5’-guanine and the 3’-guanine of the intron.d) None of the above.Q 18. Polycistronic mRNAs:a) Are found in all organisms.b) Have many introns.c) Have coding sequence for more than one polypeptide.d) Are found only in eukaryotes.Q 19. Alternative splicing is a mechanism that produces:a) Many mRNAs with the same set of exons spliced.b) More than one mature mRNAs with different combination of exons.c) Different genes.d) None of the above.Q 20. Cap structure:a) Has 7-methyl guanine.b) Found only in eukaryotic mRNAs.c) Is found at the 5’-end of mRNAs.d) All of the
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