Why do Cells Divide?The Cell TheoryThe Start of LifePotential ProblemsReproductive StrategiesAsexualAsexual in EukaryotesSexualProkaryoticChromosome StructureChromosomes in OrganismsChromatinChromatidThe Cell CycleInterphaseMitosisCytokinesisOutline of Current LectureImmortal Cells Assignment due Today!Genetic Basis of CancerOncogenesTumor SuppressorsP53Controlling Cell GrowthRegulating the Cell CycleCell Cycle check pointsCurrent LectureI. Different Cells Divide at different ratesII. The immortal HeLa Cellsa. 1st human line grown in cultureb. Revolution in a biomedical sciencec. What do cells need to grow and survive?i. Anchorageii. Nutrientsiii. Densityiv. Bio signalsIII. Cancer: a genetic diseasea. Unregulated Cell Divisionb. Genes (proteins) that control cell division are mutated of altered.IV. Cell Cycle Control Systema. Molecules that control events in the cell sycle.b. Molecules start and stop an eventi. Growth factorsii. Receptorsiii. Signaling moleculesiv. Gene regulatorsV. Controlling the Cell Cyclea. Oncogenes (gas pedal)b. Tumor Suppressors (brakes)VI. Cell Cycle Check Pointsa. G1b. G2c. Mitosis (Metaphase)VII. Tumor: Mass of abnormally growing cellsa. Benign Tumorsi. Stay at origin (Encapsulated)ii. Surrounded by normal cellsiii. Can disrupt organs and tissuesb. Malignant Tumors (cancers)i. Spread in the body (metastasis)ii. Grow blood vesselsiii. Make growth factorsiv. Can grow indefinitelyVIII. Controlling Cell Division: Treating Cancera. Localized Tumorsi. Can be removed by surgeryii. Radiation kills the cells (and surrounding tissue)b. Metastic Tumorsi. Treated with chemotherapy (poisons cells)c. Understanding genes “turn on” or “off” before they mutate.IX. Review figures:a. 8.10b. 8.8bc. 11.15bd. 11.15ae. 8.4f. 8.7bg. 8.7aBIO 105 1st Edition Lecture 7 Outline of Last Lecture Why do Cells Divide?The Cell TheoryThe Start of LifePotential ProblemsReproductive StrategiesAsexualAsexual in EukaryotesSexualProkaryoticChromosome StructureChromosomes in Organisms ChromatinChromatidThe Cell Cycle InterphaseMitosisCytokinesis Outline of Current Lecture Immortal Cells Assignment due Today!Genetic Basis of CancerOncogenesTumor SuppressorsP53Controlling Cell Growth Regulating the Cell CycleCell Cycle check pointsCurrent LectureI. Different Cells Divide at different ratesII. The immortal HeLa Cellsa. 1st human line grown in cultureb. Revolution in a biomedical sciencec. What do cells need to grow and survive?These notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.i. Anchorageii. Nutrientsiii. Densityiv. Bio signalsIII. Cancer: a genetic diseasea. Unregulated Cell Divisionb. Genes (proteins) that control cell division are mutated of altered.IV. Cell Cycle Control Systema. Molecules that control events in the cell sycle. b. Molecules start and stop an eventi. Growth factorsii. Receptorsiii. Signaling moleculesiv. Gene regulatorsV. Controlling the Cell Cyclea. Oncogenes (gas pedal)b. Tumor Suppressors (brakes)VI. Cell Cycle Check Pointsa. G1b. G2c. Mitosis (Metaphase)VII. Tumor: Mass of abnormally growing cellsa. Benign Tumorsi. Stay at origin (Encapsulated)ii. Surrounded by normal cellsiii. Can disrupt organs and tissuesb. Malignant Tumors (cancers)i. Spread in the body (metastasis)ii. Grow blood vesselsiii. Make growth factors iv. Can grow indefinitelyVIII. Controlling Cell Division: Treating Cancera. Localized Tumorsi. Can be removed by surgeryii. Radiation kills the cells (and surrounding tissue)b. Metastic Tumors i. Treated with chemotherapy (poisons cells)c. Understanding genes “turn on” or “off” before they mutate.IX. Review figures:a. 8.10b. 8.8bc. 11.15bd. 11.15ae. 8.4f. 8.7bg.
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