BBMB 405 1st Edition Lecture 1 Outline of Current LectureI. Organic ReactionsII. Use of FoodIII. Human Carbohydrate MetabolismIV. Synthesis of Major Body ConstituentsV. Key PointsCurrent LectureI. Organic ReactionsA. Dehydrogenation: loss of water from an alcoholB. Hydrolysis: reaction with water to yield a carboxylic acidC. Phosphorolysis: addition of phosphate groupD. Decarboxylation/carboxylation: loss/gain of CO2E. Hydration/dehydration: water added to yield alcoholF. Functional Groups1. Esters 2. Thioester3. Phosphoesters4. Acid: donate H+, accepts electron pair, etcThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.5. Aldehyde6. Alcohol7. Ether8. Amine9. AmideII. Use of FoodA. Food is converted to CO21. Food is digested and absorbed creating fuel molecules2. Fuel Molecules are converted to CO2 and Urea by reducing O2 and attaches a phosphate group on ADP making ATP3. ATP is used for movement, absorption, neural transmission, synthesis, and 60% is lost in heatB. Food is converted to ATP1. Fuel molecule is converted to CO2 and makes high energy molecules (FADH2 and NADH)2. Energy is used to put Pi on to ADP creating ATP3. Reduces O2 to waterC. Adenosine Triphosphate (probably a molecule we need to know)D. Metabolism = Anabolism (use ATP, make macromolecules) and Catabolism (make ATP, breakdown macromolecules)III. Human Carbohydrate Metabolism (Diagrams used in BBMB 404)A. GlycolysisB. GlyconeogenesisC. Pyruvate to Acetyl CoA D. TCA cycleIV. Synthesis of Major Body Constituents V. Key Points1. Most Amino Acids and glycerol can be used to make glucose2. All five dietary constituents can be stored as triacylglycerols3. Ethanol, fatty acids, and a few amino acids cannot be used to make glucose because acetyl-CoA cannot be converted to pyruvate and
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