UWEC BIOL 196 - Cardiovascular Disease (3 pages)

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Cardiovascular Disease



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Cardiovascular Disease

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Cardiovascular Disease, Plaque, Inflammation


Lecture number:
23
Pages:
3
Type:
Lecture Note
School:
University of Wisconsin-Eau Claire
Course:
Biol 196 - Human Nutrition
Edition:
1
Unformatted text preview:

BIOL 196 1st Edition Lecture 23 Outline of Last Lecture I Metabolism II Adipose tissue III Continuation of metabolism IV Functions of TG fat V Fat in the diet VI Phospholipids VII Cholesterol Outline of Current Lecture I Cardiovascular Disease II 7 measures of CV Health III What factors can injure the endothelium IV What is inflammation V What causes chronic inflammation VI What is plaque made of VII What causes the heart attack Current Lecture I Cardiovascular Disease These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute II III IV V a 1 in 3 Americans will die of heart disease or stroke and 60 will have a major vascular event before they die b More people die of CVD than Cancer c There is a difference between Coronary Heart Disease and CVD which contains all cardio diseases d Heart disease relates to just arteries e Prior to the 1960s people didn t know they d get a heart attack treatment began AFTER they had one f Primordial risk factors preventing from people getting risk factors like smoking weight gain etc 7 measures of CV Health a 5 of Americans meet all 7 goals b About 720 000 heart attacks 1 in 3 ends in death i Often a result of atherosclerosis c How to develop atherosclerosis i Injury to endothelial cells lining of artery wall ii Followed by inflammation iii And plaque formation What factors can injure the endothelium a High LDL b Smoking c Diabetes d High blood pressure uncontrolled e Virus bacteria f Physical injury g Chronic inflammation What is inflammation a Body s response to an injury immune response physical or chemical injuries b External injuries burns bruises sprains fractures etc i Acute inflammation ii Response redness swelling pain heat trying to kill off possible bacteria What causes chronic inflammation a Injury to the artery wall from various chemicals physical damage from i Obesity and metabolic syndrome ii High blood pressure iii Smoking iv Atherosclerosis v Diabetes vi High LDL low HDL special types of LDL b Internal i Blood vessel injury ii Injury to the endothelium VI VII 1 Monocytes white blood cells imbed in the injured site artery wall 2 Take up eat oxidized LDL and other components that are part of plaque What is plaque made of a How do you know if you have chronic i For people who want a test C reactive test is available ii 50 of heart disease occurs in people with low blood cholesterol 1 Not just a LDL problem What causes the heart attack a Inflammation plaque and protein rupture clot formation b Blood clots lead to heart attacks c The atherosclerosis process can begin in early childhood d War autopsies Korean war average age of death was 22 years i 78 had plaque accumulation at age 22 1 Smoking a major factor e Bogalusa L A heart study since 1972 i 17 000 kids ii 200 autopsies ages 2 39 car accidents etc iii Anatomical changes occur by 5 8 years iv Fatty streaks earlier than age 5


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