CU-Boulder IPHY 2420 - Epigenetics (4 pages)

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Epigenetics



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Epigenetics

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Lecture number:
32
Pages:
4
Type:
Lecture Note
School:
University of Colorado at Boulder
Course:
Iphy 2420 - Nutrition for Health and Performance
Edition:
1

Unformatted text preview:

IPHY 2420 1st Edition Lecture 32 Outline of Last Lecture Eating Healthy Over The Holidays Current Lecture Easy day Testable Clicker Questions Outline of Current Lecture December 1 2014 1 Epigenetics 2 Bioactive Food Components 3 Future Generations 4 The Dutch Hunger Winter 5 Relationships with other Starvation events Current Lecture 1 Epigenetics Mother 1st Generation smoking effects all the way down Fetus 2nd Generation smoking effects all the way down Reproductive Cells 3rd generation Your food choices influence what genes are turned on and the way you age and what diseases you are prone too Epigenome Proteins and other molecules that regulate expression of genes o Turning genes on and off o Inherited or altered These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute Regulation mechanisms what turns them on and off o Histones o Methyl Groups 2 Bioactive Food Components a Nutrient or Phytochemical is generated during metabolism and decides what genes are activated or silenced food directs on and off switch b Protein Synthesis increased or decreases c Changes cell and tissue functioning d Disease prevention or progression e EVEN WHEN YOU ARE 20 food influences the future 3 Future Generations Embryonic development What you eat if you are under stress like starvation then you are impacting the next 2 generations if your grandmother went through a starvation event you may be more likely to have a higher body mass Modification of epigenome Health Impacts Bioactive constitutes in whole foods EXAMPLE The Dutch Hunger Winter o Germans cut off food supplies for the Dutch to starve them out so they would surrender o Calories reduced to 500 1000 calories per person as opposed to 2000 calories o Altered genetics of babies 311 women were pregnant o There kids were prone to obesity and heart disease then siblings before or after famine ALL 311 babies Thrifty Gene Native Americans o



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