UT Arlington NURS 3365 - Key Concepts HTN and diuretics (3 pages)

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Key Concepts HTN and diuretics



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Key Concepts HTN and diuretics

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Pages:
3
School:
University of Texas at Arlington
Course:
Nurs 3365 - Pharmacology in Nursing Practice
Pharmacology in Nursing Practice Documents

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Key Concepts Antihypertensive drugs and Diuretics Types of hypertension o Primary o Secondary o Malignant hypertension Goal of antihypertensive drug therapy Cardiac output and blood pressure o Vasoconstriction increased afterload and preload o Sodium retention increased preload o Increases SNS activity increased contractility and HR Terms o Inotrope o Dromotrope o Chronotrope Beta blockers o See ANS key concepts for basics o Why would a beta blocker be used to treat HTN o Kinetics large first pass effect why is this important to know o CYP inhibitors can increase level of beta blockers o Drugs that could inhibit effect of beta blockers o Drugs that could potentiate effect of beta blockers o Caution in patients having allergy testing or who have allergic conditions o Caution in diabetics o Proactivity Alpha 1 blockers o See ANS key concepts o Why might patients taking this drug develop nasal congestion o Why might they develop edema o What type of sexual dysfunction could occur with this drug o Proactivity Teach to move slowly Alpha 2 agonists See ANS key concepts ACE inhibitors o Action and effect Accumulation of bradykinin why is this important o Used to treat HTN CHF and protect kidneys in renal failure How does it protect kidneys o Side effects First dose effects Common side effects Serious side effects o Drug interactions K sparing diuretics Potassium supplements Other antihypertensive drugs Proactivity Teach Assess Prevent pregnancy ARBs o How do they differ from ACE inhibitors Calcium channel blockers o Dihydropyridines versus nondihydropyridines o Uses o Side effects Must know side effects that are particular to each subclass of calcium channel blockers Dihydros dilate only thus low BP edema Nondihydros dilate and affect node so more cardiac side effects o Proactivity Teach Assess Diuretics o Loops thiazides potassium sparing o All inhibit reabsorption of sodium Causes excess water to leave body Decreases preload o Loops Action and effect Sulfonamide molecule



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