UNT BIOL 3451 - Genomics, Bioinformatics, and Proteomics (4 pages)

Previewing page 1 of 4 page document View the full content.
View Full Document

Genomics, Bioinformatics, and Proteomics



Previewing page 1 of actual document.

View the full content.
View Full Document
View Full Document

Genomics, Bioinformatics, and Proteomics

362 views

Finished up sequencing techniques and began discussing genomics, bioinformatics, and proteomics.


Lecture number:
27
Pages:
4
Type:
Lecture Note
School:
University of North Texas
Course:
Biol 3451 - Genetics
Edition:
1
Documents in this Packet

Unformatted text preview:

BIOL 3451 1st Edition Lecture 27 Outline of Last Lecture I 20 2 DNA Libraries Are Collections of Cloned Sequences II 20 3 The Polymerase Chain Reaction Is a Powerful Technique for Copying DNA III 20 4 Molecular Techniques for Analyzing DNA IV 20 5 DNA Sequencing Is the Ultimate Way to Characterize DNA Structure at the Molecular Level Outline of Current Lecture I 20 5 DNA Sequencing Is the Ultimate Way to Characterize DNA Structure at the Molecular Level II 21 1 Whole Genome Shotgun Sequencing Is a Widely Used Method for Sequencing and Assembling Entire Genomes III 21 2 DNA Sequence Analysis Relies on Bioinformatics Applications and Genomic Databases IV 21 3 Functional Genomics Attempts to Identify Potential Functions of Genes and Other Elements in a Genome V 21 4 The Human Genome Project Reveals Many Important Aspects of Genome Organization in Humans Current Lecture I 20 5 DNA Sequencing Is the Ultimate Way to Characterize DNA Structure at the Molecular Level o dideoxynucleotide chain termination sequencing Sanger sequencing used to be the most common DNA sequencing that was developed by Sanger Fig 20 15 and 20 16 Involves addition of a small amount of one modified deoxyribonucleotide called dideoxynucleotide which causes DNA synthesis to terminate This caused Gilbert s technique to fall to the way side Now Sanger s not used much anymore o Computer automated high throughput DNA sequencing Since early 1990s DNA sequencing has largely been done through computer automated Sanger reactionbased technology Generates large amounts of sequence DNA Enabled the rapid progress of the Human Genome Project These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute II Large scale genome sequencing is automated and uses fluorescent dyelabeled dideoxynucleotides Fig 20 16 and 20 17 o Next generation sequencing NGS technologies allows faster and cheaper genomic sequencing to take place Now



View Full Document

Access the best Study Guides, Lecture Notes and Practice Exams

Loading Unlocking...
Login

Join to view Genomics, Bioinformatics, and Proteomics and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view Genomics, Bioinformatics, and Proteomics and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?