UMass Amherst NUTRITN 130 - Free Radicals (3 pages)

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Free Radicals

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Free Radicals


This lecture covered Free Radicals and how they effect the body, their functions and what they cause and how they are formed.

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University of Massachusetts Amherst
Nutritn 130 - Nutrition for a Healthy Lifestyle
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Nutrition 130 1st Edition Lecture 20 Learning Objectives Know what causes the formation of free radicals Know diseases associated with free radical change Describe how antioxidants help in cancer and CHD prevention Identify the modifiable risk factors of cancer Know dietary recommendations to reduce cancer risk Identify which nutrients function as antioxidants and identify their functions outside of antioxidant function food sources and diseases of deficiency Know the increased needs of smokers for antioxidants Know benefit risk of antioxidant supplements Free Radicals Atom with an extra unpaired election forms a free radical o Are molecules that are unstable ATP is the energy currency of the body How Free Radicals are Formed Oxidation reduced reactions normal cell processes Pollution Ultraviolet light and radiation tanning Toxic substances Free Radical Damage Cell membranes are damaged Low density lipoproteins LDLs Proteins in the cell Genetic material DNA These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute Disease related to Free Radicals Cancer Heart Disease Eye disease o Cataracts o Age related macular Parkinson s Antioxidants A compound that has the ability to prevent or repair the damage caused by oxidation Antioxidant Micronutrients Vitamin E Vitamin C Beta Carotene Vitamin A may have antioxidant properties Copper iron zinc manganese Cardiovascular disease Antioxidants may reduce the risk of CVD by o Preventing free radical damage oxidation of LDL cholesterol o Acting as an anticoagulant to prevent blood clots o Reduce inflammation Cancer development Normal cell initiation promotion further tumor development malignant cells Causes initiation and Promotion Tobacco Sun exposure Diet Toxins occupational exposure Low physical activity Antioxidants can stop initiation and promotion Antioxidants also Enhance immune system Inhibit growth of cancer cells Prevent oxidative damage to cells

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