Pitt NROSCI 0080 - Exam 3 Study Guide (8 pages)

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Exam 3 Study Guide

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Exam 3 Study Guide


Study Guide
University of Pittsburgh
Nrosci 0080 - Brain and Behavior
Brain and Behavior Documents

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NROSCI 0080 1st Edition Exam 3 Study Guide What are the two major types of stroke Which type is generally more severe and less treatable Which type can often be treated with t PA tissue plasminogen activator o Ischemic Stroke lack of blood flow to the brain usually due to a clot o More treatable less severe T PA breaks down the clot Hemorrhagic Stroke burst vessel bleeding into the brain Usually results in an ischemia downstream of the hemorrhage T PA would be disastrous if administered to a patient suffering from a hemorrhagic stroke Why has the documented incidence of Alzheimer s disease increased sharply during the past 100 years o The average life span is much longer o In Alzheimer s disease what are the plaques and tangles Do these ever appear in the brain of healthy normally aging individuals o Plaques accumulation of unprocessed A beta protein usually present in a smaller cleaved form o Tangles intracellular tangles of cytoskeletal elements in dead neurons o Not usually seen in the brains of healthy individuals How can PET imaging help to diagnose Alzheimer s disease o Our diagnostic abilities have sharpened Plaques can be detected with PET images with Pittsburgh Compound Describe explicit and implicit memory How are they related to procedural and declarative memory o Explicit Declarative memories of people things events etc o Knowing that Implicit Non declarative memories of how to do things motor memory not consciously aware of Knowing how to Describe episodic memory o Memory of autobiographical events o Emotional What are the three stages of memory o Immediate seconds o Short Term minutes hours Can be maintained through rehearsal o Long Term lifetime What are the neural circuits for implicit explicit and emotional memory o o o Implicit Sensory motor information neocortex basal ganglia ventral thalamus premotor cortex Modulated by dopamine Explicit Sensory motor information rest of neocortex temporal lobe prefrontal cortex medial thalamus feedback mechanism

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