DOC PREVIEW
ISU BSC 160 - Diseases
Type Lecture Note
Pages 3

This preview shows page 1 out of 3 pages.

Save
View full document
View full document
Premium Document
Do you want full access? Go Premium and unlock all 3 pages.
Access to all documents
Download any document
Ad free experience
Premium Document
Do you want full access? Go Premium and unlock all 3 pages.
Access to all documents
Download any document
Ad free experience

Unformatted text preview:

Lecture 33Outline of Last Lecture 1. Infections2. Invasions3. Diseases to knowOutline of Current Lecture 1. Streptococcal Disease2. Tuberculosis3. Influenza VirusesCurrent LectureStreptococcal DiseasesMethod of pathogenesis- Fimbrae- Exoenzyme- for invasion, movement beyond attachment- Capsules- similar to host’s own components, hides bacteria. o Complement system is about antibody binding, bringing about changes  Causing hole. Antibodies don’t recognize capsules. Complement system not as effective- Creation of super antigen: toxin able to bind to regions other than antigenic site and still stimulate T cells. Controlled response to specific antigen. o *1/5 T cells activated by these antigensTreatment: Penicillin, vaccineStaphylococcus aureus- Microbe. Gram+/-, disease, method of pathogenesis, treatmentMycobacterium- Tuberculosis. - 1900’s major cause of death in humans- 100% of population infected, 25% dying- Large rod, motile, hydrophobic- Obligate anaerobe, has to have air BSC 160 1nd Edition- Slow growth, generation time is 15-20 hours - Grows/reproduces in extracellular fluid (macrophages) Difficult to detect and treat Method of Pathogenesis- Does NOT have classic virulence factors- Enters phagocytes: Lets it get eaten, doesn’t go away- Synthesizing highly negative recharged sugar coat, prevents fusion of phagosome and lysosome - Antibiotics are repelled bc so hydrophobic, antibodies repelled- Capable of killing macrophage it is inTreatment- No single treatment, 6-9 month treatment, 95% cure rate- 4 drugs, drug synergy- Vaccine, injection, prevents from getting disease but not infection- If been vaccinated, positive reading on TB test- 60-80% effectiveClostridium sp./ Corynebacterium diptheriaeMicrobe, disease, pathogenesis, treatmentFungal InfectionsCold and Flu Viruses- Infection: Nose- Common Cold- most common viral infection- Colds per year= 1 Billion- 2-3 days after infection, runny nose, headache. Go away after about 9 days- Protein capsid, +SSRNA- Small, simpleTreatment- Let cold run its course, over the counter meds to feel better- No vaccine- Vitamin C doesn’t make a differenceRepiratory Tract- mucosa Influenza Viruses1. Type A- Organized into diff types, based on what HA it has- And what NA it has- H1N1- Mostly respiratory disease. Fall & Winter - 42 hour incubation period- If completely unprotected, not common cold- Pig fever, chills, muscle aches, can become lower respiratory2. Type B3. Type CTreatment- Supportive care- Antiviral drugs, depends on when exposed & when you have access to


View Full Document

ISU BSC 160 - Diseases

Type: Lecture Note
Pages: 3
Documents in this Course
Load more
Download Diseases
Our administrator received your request to download this document. We will send you the file to your email shortly.
Loading Unlocking...
Login

Join to view Diseases and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view Diseases 2 2 and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?