Life Sciences 2 Life Sciences 2: Cells, Tissue, and Organ Systems Spring 07 Instructor: Youssef Ezzeddine, Ph.D. 2524 Gonda, (310) 600-5799, [email protected] Office Hours: Mon 10:00-12:00, TBA TAs: Sara Chalifoux ([email protected]) Renee Chen ([email protected]) Mikhail Faybyshev ([email protected]) Rana Khankan ([email protected]) Diana Shy ([email protected]) Elizabeth Wong ([email protected]) Mike Wygant ([email protected]) Class Time: Mon, Wed, & Fri 9:00 - 9:50 am, Moore 100 Website: http://www.lsic.ucla.edu/classes/ http://lslab.lscore.ucla.edu/ Lab Management: Dr. Gaston Pfuegl. YHS 2340, 44113 ([email protected]) LS Administrator: Lily Yanez. LSB 2305, x56614 ([email protected]) Mark Katayama. LSB 2305, x56614 ([email protected]) Textbook: Purves, Orians, and Heller, Life, The Science of Biology, 8th edition. Sinauer Associates, Inc.; Sunderland, Freeman and co. The textbook will be on reserve in the Powell Library. Life Sciences 2, Laboratory Manual, 5th edition. Available at ASUCLA Bookstore. Grading: Total points for this class will be 500 points: Midterm 1 (Thursday 4/19/07; 5-7 pm) 100 points Midterm 2 (Thursday 5/10/07; 5-7 pm) 100 points Lab Experiments and quizzes 80 points Lecture Assignments 40 points Attendance and Participation 10 points Final Exam (Wed 6/13; 6:30-9:30 pm) 170 points (20 points from the lab will be on the final exam) Total: 500 pointsExams: Two midterm examinations will be held on Thursday 4/19 and Thursday 5/10 (5-7 pm) location TBA. The final exam will be held on Wed 6/13 (6:30-9:30 pm). Examinations will cover material from the lecture, reading, and discussion sections. The lecture component of the final exam is cumulative. All the exams will have both multiple choice type questions and short answers type questions. Requests for regrades must be submitted in writing with a detailed explanation and justification within one week after the exams have been graded. Make-up Policy: No make up examination will be given. If you are unable to take an examination due to illness or other emergency, you are responsible for contacting the Life Sciences Core Curriculum Office (LSB 2305, 310 825-6614) before the examination. You are required to have written verification from a physician or parent regarding the illness or emergency. Lecture notes: Lecture notes are available on the class webpage (www.lsic.ucla.edu/classes). Make sure you download the lecture notes before coming to class. Having the lecture notes with you will facilitate taking notes in class. Discussion Section: Attendance to the weekly discussion/lab sections is an important component of the course. Assigned papers (read below) will be discussed during each section. Weekly assignments pertaining to the papers will be posted on the class webpage the Friday before the first discussion section meeting on Monday. Assignments must be turned in at the beginning of each section. All assignments must be turned in on time. Late assignments will not be accepted. The discussion sections will concentrate on experimental issues and problem sets that will help you understand the lecture and succeed when taking the exams. Some of the questions on the exams will come from the discussion sections. Thirty percent of your final grade comes from discussion section, lab, attendance, written assignments, and class participation. Lecture material and papers will be presented in discussion sections. Attendance to the discussion and lab sections is mandatory. Tardiness and absences will not be tolerated. If you are late or absent from the discussion section you will not get participation points. Assigned Papers: 1- Discussion 1 (4/9-4/13) How Cancer Arises. Robert A. Weinberg. Scientific American, September 1996, Vol. 275 Issue 3, p62, 9p Assignment will be posted on the course webpage on Friday 4/6. 2- Discussion 2 (4/23-4/27) Building a Brainier Mouse. Joe Z. Tsien. Scientific American, April 2000, Vol. 282 Issue 4, p62, 7p Assignment will be posted on the course webpage on Friday 4/20.3- Discussion 3 (5/7-5/11) Infectious Diseases and the Immune System. Paul E. William, Scientific American, September 1993, Vol. 269 Issue 3, p90, 8p Assignment will be posted on the course webpage on Friday 5/4/07. 4- Discussion 4 (5/29-6/1) Cystic Fibrosis. Michael J. Welsh and Alan E. Smith. Scientific American, December 1995, Vol. 273 Issue 9, p52, 8p Assignment will be posted on the course webpage on Friday 5/25. Instructions to download papers: These instructions will work from on-campus computers only or on computers that has Bruin On Line Proxy Server Set Up. Go to http://www2.library.ucla.edu Place mouse cursor on Search and Find Move mouse cursor to E-resources Click on E-Journals On the Search for e-journals titles, type Scientific American and hit enter From the right side menu, select v.268 (1993) Scientific American Archive, Restricted to UC campuses Type in the title of the desired article in the find box Undergraduate Research Initiative (UCLA IRB #G06-09-079-01): This is the first quarter we will introduce a research module into LS2. The Undergraduate Research Initiative at UCLA (URI) aims at bringing research to undergraduates, such as you, students in LS2. In the URI, students learn about cutting-edge research in various fields of sciences by experiencing it. The URI is not a course; it is a collaboration. Students in different undergraduate courses – from general education science to upper division life sciences – participate and learn while building a major research accomplishment. The specific aims of this current project are two-fold: The first aim is to provide undergraduate students with a database through which they can understand research design. The current project proposes to assess cognitive functioning of undergraduate students through sophisticated computerized measures developed by a neuropsychologist, the Memory Interference Test (MIT). This will allow students to experience how real research studies are conducted and understand the