Progress Report Week 11: Week of November 13th to November 19th 2008 Liver Phantom for MRI Guided Trans-arterial Chemoembolization Simulation Client: Dr. Wally Block Ph.D. University of Wisconsin – Biomedical Engineering Department Advisor: Dr. William Murphy Ph.D. University of Wisconsin – Biomedical Engineering Department Team: Benjamin Engel, Leader Ryan Carroll, BWIG Eric Printz, Communicator Justin Schmidt, BSAC Problem Statement Liver cancer treatment can often involve higher, more targeted doses of chemotherapy if delivered directly to the liver. Professor Block’s MRI lab is integrating capabilities to guide cancer treatment to the liver using magnetic resonance imaging. Current x-ray treatments significantly over treat the liver because while x-ray can be useful in the visualization of catheters, they can't visualize soft tissue, specifically the tumor. It is proposed to develop a liver phantom that will simulate the arterial vessels of the abdomen as well as the liver in an effort to simulate treatments and train interventional radiologists on the use of the new MRI guided techniques. The project will include adding flow capabilities through the use of a programmable fluid pump to simulate pulsatile flow. Week 11 Goals • Create and finish vasculature (depending on arrival of parts) • Begin/finish creation of enclosure • Once finished begin mounting connectors and vasculature within enclosure • Build amplification circuit on LJ Proto Board for future use • Study software that arrives with LabJack to determine how to program analog sinusoidal waveforms to the analog output terminal (may require coding in C) Week 11 Activities Team Member Accomplishments Hours Running Total (Hours) Benjamin Engel Vasculature construction, enclosure construction, helped develop parts list, team meeting 10 50.5 Ryan Carroll Team meeting, vascular creation, helped develop parts list, enclosure construction 10 53.5 Justin Schmidt Vasculature construction, helped develop parts list, enclosure construction, team meeting 10 50.5 Eric Printz Vasculature construction, enclosure construction, developed parts list, meet with advisors at hospital for advice, placed orders 12 52Week 11 Accomplishments • Finalized vasculature and determined exact spatial relations within the phantom • Cut sides for enclosure, determined location of inlets and outlets, drilled all holes for inlets and outlets, and adhered sides together to create enclosure • Bought remaining necessary connectors and tubing to finalize phantom and interface device with existing tubing running to and from MR control room • Discussed progress with client • Scheduled tentative scan time on Dec. 1st and 2nd Week 12 Goals • Caulk enclosure walls to seal • Attach all connectors to enclosure wall • Mill a notch in the lid so that it slides nicely over the top of the enclosure • Create seal on top of box and attach latches which close the cover • Test vasculature with flowing water • Connect vasculature to inside of phantom and seal all connections • Attach entire unit to pump to test integrity of device Schedule Scheduled Completed Monday of Required Presentation 9/1 9/8 9/15 9/22 9/29 10/6 10/13 10/20 10/27 11/3 11/10 11/17 11/24 12/1 12/8 12/15 Propose project Conduct background research Discuss parameters w/ client Develop PDS Brainstorm/solidify design ideas for initial prototype Midsemester presentation Order materials Construct prototype Safety Testing/improvements Usability Testing w/ interventional radiologists Final Presentation Preparation Final PaperProject Difficulties • Labjack equipment has not yet arrived. It is likely that pulsatile flow will be put off to next semester or implemented over winter break. Expenses • Currently do not have detailed list of expenses. This will be added at a later
View Full Document
Unlocking...