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ECU BIOL 1050 - Human Genetics
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BIOL 1050 1st Edition Lecture 19 Outline of Last LectureI. ReviewII. BackgroundIII. MeiosisIV. Genetic uniquenessa. Random fertilizationb. Crossing overV. Genetics background Outline of Current LectureI. Human GeneticsCurrent LectureI. Human geneticsa. Dominant traitsb. Recessive traitsc. Examples of single-gene traitsi. Cleft chin/non-cleft chinii. Unattatched earlobes/attatched earlobesiii. Widows peak/straight hairline d. Disorders controlled by a single, autosomal genei. Many human disorders are controlled by a single gene, on autosomesii. Most genetic diseases are recessiveiii. Carriers have 1 recessive allele for disease, but no symptomse. Punnett squares are used to see the probability of two people passing on certain traits to offspringf. Dominant Disordersi. Lethal dominant disorders are rare because:1. Those afflicted usually die before reproducing (including heterozygotes)ii. Lethal dominant disorder can remain if it doesn’t kill until after person has kidsg. Huntington’s Diseasei. Mother is homozygous (hh) with 2 copies of the normal allele (h)ii. Father is heterozygous (Hh) with 1 copy of the huntington’s allele (H)iii. Result of punnett square: Hh, Hh, hh, hhThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.1. Children of the cross have ½ chance of having Huntington’s disease2. ½ chance the child will be


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ECU BIOL 1050 - Human Genetics

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