Chapter 26, part 3SECTION 26-5 Renal Physiology: Reabsorption and SecretionReabsorption and secretion at the PCTFigure 26.12 Transport Activities at the PCTThe loop of Henle and countercurrent multiplicationFigure 26.13 Countercurrent Multiplication and Concentration of UrineSlide 7Slide 8Reabsorption and secretion at the DCTFigure 26.14 Tubular Secretion and Solute Reabsorption at the DCTSlide 11Reabsorption and secretion along the collecting systemControl of urine volume and osmotic concentrationFigure 26.15 The Effects of ADH on the DCT and Collecting DuctsSlide 15Function of the vasa rectaComposition of normal urineSummary of renal function:Figure 26.16 A Summary of Renal FunctionSlide 20Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Fundamentals of Anatomy & PhysiologySIXTH EDITIONFrederic H. MartiniPowerPoint® Lecture Slide Presentation prepared by Dr. Kathleen A. Ireland, Biology Instructor, Seabury Hall, Maui, HawaiiChapter 26, part 3The Urinary SystemCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsSECTION 26-5 Renal Physiology: Reabsorption and SecretionCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings•Glomerular filtration produces fluid similar to plasma without proteins•The PCT reabsorbs 60-70% of the filtrate produced •Reabsorption of most organic nutrients•Active and passive reabsorption of sodium and other ions•Reabsorption of water•Secretion also occurs in the PCTReabsorption and secretion at the PCTAnimation: Early Filtrate ProcessingPLAYAnimation: Glomerular filtrationPLAYCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.12 Transport Activities at the PCTAnimation: Proximal Convoluted TubulePLAYFigure 26.12Copyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsThe loop of Henle and countercurrent multiplication•Countercurrent multiplication •Between ascending and descending limbs of loop•Creates osmotic gradient in medulla•Facilitates reabsorption of water and solutes before the DCT •Permits passive reabsorption of water from tubular fluidCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.13aFigure 26.13 Countercurrent Multiplication and Concentration of UrineCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.13bFigure 26.13 Countercurrent Multiplication and Concentration of UrineCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.13cFigure 26.13 Countercurrent Multiplication and Concentration of UrineCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings•DCT performs final adjustment of urine•Active secretion or absorption•Absorption •Tubular cells actively resorb Na+ and Cl- •In exchange for potassium or hydrogen ions (secreted) Reabsorption and secretion at the DCTCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.14Figure 26.14 Tubular Secretion and Solute Reabsorption at the DCTAnimation: Distal Convoluted TubulePLAYCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.14cFigure 26.14 Tubular Secretion and Solute Reabsorption at the DCTCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsReabsorption and secretion along the collecting system•Water and solute loss is regulated by aldosterone and ADH•Reabsorption•Sodium ion, bicarbonate, and urea are resorbed•Secretion •pH is controlled by secretion of hydrogen or bicarbonate ionsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsControl of urine volume and osmotic concentration•Urine volume and osmotic concentration are regulated by controlling water reabsorption•Precise control allowed via facultative water reabsorptionCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.15Figure 26.15 The Effects of ADH on the DCT and Collecting DuctsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.15a, bFigure 26.15 The Effects of ADH on the DCT and Collecting DuctsCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings•Removes solutes and water •Balances solute reabsorption and osmosis in the medullaFunction of the vasa rectaCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings•Varies with the metabolic and hormonal events of the body•Reflects filtration, absorption and secretion activity of the nephrons•Urinalysis is the chemical and physical analysis of urineComposition of normal urineCopyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings•Each segment of nephron and collecting system contribute•Glomerulus•PCT•Descending limb •Thick ascending limb •DCT and collecting ducts•Concentrated urine produced after considerable modification of filtrateSummary of renal function:Animation: Late Filtrate ProcessingPLAYCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.16 A Summary of Renal FunctionFigure 26.16aCopyright © 2004 Pearson Education, Inc., publishing as Benjamin CummingsFigure 26.16 A Summary of Renal FunctionFigure