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Berkeley
STATISTICS 246 -
Multiple sequence alignment and phylogenetic trees
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1Multiple sequence alignment andphylogenetic treesStat 246, Spring 2002, Week 5b2A version of the “tree of life”Obtained from aligned sequences of ribosomal RNA3Species trees and gene trees(after M. Nei 1987, Molecular Evolutionary Genetics.)AA ABB BX Y Z X Y Z X Y ZTimeGenes can be polymorphic before speciation, in different ways.4Tree topologyA E C D B F A E D C B FA E C D B F F B D C E AIdentical:Notidentical:5Tree reconstructionA B C B A C C A B6Tree reconstruction (2)A C B D B C A D C D A B D C A BA B C D B A C D C B A D D B C AA D C BB D C A C A B D D A B CA B C DA C B DA D B
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