University of California, San Diego Syllabus - Structural Biochemistry BIBC 100 – Summer 05 Lecture MW 2:00p - 4:50p CENTR 109 Makeup F 07/01/2005 2:00p - 4:50p CENTR 109 Final S 07/30/2005 11:30a - 2:30p CENTR 109 Week Day Lecture topics Reading * Comments 1 M 6/27 Introduction Aqueous solutions Amino acids 1.3 2, 8.4 4 W 6/29 Protein secondary structure X-ray and NMR techniques 7.1, 8 F 7/1 DNA and RNA structures 5, 29, 32 Makeup session 2 M 7/ 4 Holiday -- W 7/6 Polysaccharides Cell membranes 11 12 Quiz 1 3 M 7/ 11 Enzymes: Serine proteases Binding: Hemoglobin Metal binding proteins 13.2, 13.4 15.3 10, 15.1, 18.3 W 7/13 Ion channels Electron transport 20, 12.3, 9.3 24.2 Midterm 4 M 7/18 Protein motion Protein folding Protein stability 9, 20.2 8.4 34.4 W 7/20 Nucleosome structure DNA binding proteins 34 31.3 5 M 7/25 Molecular motors Glycoproteins, antibodies 20.3, 22.3 11.3 Quiz 2 W 7/27 Receptors HIV and drug design 19.2, 19.3, 22.315.4 S 7/30 FINAL 11:30 – 2:30 PM Final Reading: Chapters from Voet & Voet, Biochemistry, 3rd ed, 2004; Many times only a part of a book chapter is covered; please refer to lecture notes, slides, and reader for the proper selection; required reading from Class Reader (Structural Biochemistry, Second edition by Lukas K. Buehler Publisher: J.Wiley & Sons (custom reader; ISBN: 0471447749); Lecture information and slides at class web site: http://www.biology.ucsd.edu/classes/bibc100.SU05.1/ Grading: Midterm and Final exam 40% each, Quiz 1 and 2 10% each; final is not cumulative Grade A (90% of total), B (80%), C (70%), D (60%) TA sections: A01 T 1:00-1:50 PM Peter 103 A02 Th 1:00-1:50 PM Peter 103 A03 F 11:00 AM - 12:50 PM WLH 2207 A04 MW 10:00-10:50 AM Sequoia 147 Contacts: Dr. Lukas Buehler [email protected] OH W 12:30-1:30PM Bonner Hall 2238 Rina Fong [email protected] Kyle Lacy [email protected] regarding exams and regrading Regrading Regrades for midterms will be allowed and have to be submitted no later than one week from the time you receive the graded exams. It is the responsibility of TAs grading a particular problem to make corrections or adjustments. You can submit a written request for more than one problem. Those requests will be regraded during a regrading session after the one week period allotted to submit a request. Make up exams Midterms are held during class time. Makeup exams are available for emergency reasons and conflicts with other assignments for which students have no control over the timing. For conflicts regarding the final exam and having more than two (=3) final exams within a 24-hour period, you need to contact your college administration to request make up exams. You should do this during the first week of class and as soon as you are aware of such clustering. There are no makeup finals if you (or some relatives) make travel arrangements before the end of the scheduled final exam. Cheating To avoid cheating problems, please write in pen and not pencil. If you make changes, mark them clearly (cross out) and do not erase and write over other words. A small number of exams will be photo copied (after grading and before students receive them) and compared with the submitted regrade request. Photocopies are done randomly and are not a systematic approach nor are they targeting any students in particular. Cheating will be reported to the Dean of your
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