ENGG 167 - Syllabus MEDICAL IMAGING Offered: F06 A comprehensive introduction to the major aspects of standard medical imaging systems used today. Topics include radiation-interaction, radiation damage and risk, x-ray imaging, computed tomography, image reconstruction and analysis, nuclear medicine, MRI, ultrasound and imaging applications in therapy. The fundamental physics and engineering underlying each imaging modality are reviewed and an performance analysis approach to each system is examined. The class involves significant laboratory work to give the student experience in several different imaging systems available at the Medical Center. Evaluation is based upon tests, labs, as well as journal club review of research papers and commercial equipment. Pre-requisite courses: ENGS 23 or permission of instructorLecture Schedule (assuming 3 lectures per week of 65 minutes each) 1. Ionizing Radiation (3 lectures) 1.1 Radiation & interaction with matter 1.2 Radiation dosimetry, risk and protection 1.3 Radiation Biology 2. Radiography (2 lectures) 2.1 Film-screen and digital 2.2 Mammography & Fluoroscopy 3. Ultrasound Imaging (US) (2 lectures) 4.1 Principles of US 4.2 Practice of US 4. Image Analysis (4 lectures) 4.1 Image Analysis 4.2 Image Processing I- image types and linear transforms 4.3 Image Processing II – frequency analysis 4.4 Fourier Filtering 5. Computed Tomography (3 lectures) 5.1 Image reconstruction theory 5.2 Computed Tomography (CT) systems 5.3 ROC Analysis 4. Mid term test (after class hours) 6. Magnetic Resonance Imaging (MRI) (6 lectures) 6.1 Principles of NMR 6.2 MR imaging 6.3 MR Imaging 6.4 MR pulse programming 6.5 MRS & fMRI 6.6 Applications of MR 7. Nuclear Medicine Imaging (2 lectures) 7.1 Single Photon Emission Computed Tomography (SPECT) 7.2 Positron Emission Tomography (PET) 8. Imaging applications in Therapy (3 lectures) 6.1 Radiation therapy treatment planning 6.2 Conformal therapy / Bracheytherapy 13. Final Exam (exam period) Total lectures = 25Journal article review sessions: Monthly journal club participation is required. There will be 2 of these sessions total. There will also be two sessions devoted to reviewing companies in medical imaging. The format is that each student reads and summarizes a research paper or literature from a company related to medical imaging, and then presents the summary to the class. Presentation time is restricted to 10 minutes, of which half is reserved for questions. Potential journals to select articles are: IEEE Transactions in Medical Imaging, IEEE Transactions in Biomedical Engineering, Physics in Medicine and Biology, Medical Physics, Radiology, Radiation Research, Int. J. Radiat. Oncol. Biol. Phys. Company selections for review will be given out in class, but generally are taken from advertisers in Medical Physics. (links to these are on the course website). Overall Evaluation: Labs & Problem sets 50% mid-term test 15% journal reviews 20% Exam 15% Course Text: The Essential Physics of Medical Imaging, 2nd Edition, (2002) by J. T. Bushberg, J. A. Seibert, E. M. Leidholdt, J. M. Boone, Lippencott Williams & Wilkins Pulb. (Kluwer), Additional Resource Texts: 1) The Physics of Medical Imaging, S. Webb, Institute of Physics Publishing, 1988. 2) Christensen's Physics of Diagnostic Radiology by Thomas S. Iii Curry, James E. Dowdey, Robert C., Jr Murry, Lea & Febiger Publishing, 4th edition, 1990. 3) Introduction to Radiological Physics and Radiation Dosimetry, F. H. Attix, John Wiley and Sons Publishing, 1986. 4) Medical Physics and Biomedical Engineering, B. H. Brown, R H Smallwood, D C Barber and D R Hose, Institute of Physics Publishing Ltd., 1999. 5) The Modern Technology of Radiation Oncology, J. van Dyk, Medical Physics Publishing, 1999. 6) Radiobiology for the Radiologist, Eric J. Hall, Lippincott Williams & Wilkins, 5th edition,