UCSD BILD 1 - Lecture (17 pages)

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Lecture



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Lecture

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Lecture Notes


Pages:
17
School:
University of California, San Diego
Course:
Bild 1 - The Cell
The Cell Documents

Unformatted text preview:

Which of the following represents the correct order of enzymes that replicate the lagging strand of DNA A Primase helicase DNA Polymerase III DNA Polymerase I ligase B DNA Polymerase I DNA Polymerase III helicase primase ligase C Helicase primase DNA Polymerase III DNA Polymerase I ligase D Ligase primase helicase DNA Polymerase III DNA Plymerase I Bacterial Replica on origin h2p highered mcgraw hill com classware ala do isbn 0072464631 alaid ala 661234 showSelfStudyTree true Each new DNA strand can be synthesized only in 5 3 direction synthesis of this strand must con nue in the direc on opposite to the direc on of the replica on fork Each replication fork consists of a strand that is replicating continuously leading strand and a strand that is replicating discontinuously lagging strand In eukaryotic chromosomes replication starts at multiple replication forks are expanding in both directions Replicating fly DNA Pictures 1 2 and 3 show how the same por on of DNA would appear at di erent stages of replica on In Eukaryotes DNA exists in complex with proteins This complex is called Chroma n Nucleosome 10 nm in diameter DNA double helix 2 nm in diameter H1 Histones DNA the double helix Histones Histone tail Nucleosomes or beads on a string 10 nm fiber Histones are proteins that are responsible for the rst level of DNA packing in chroma n Fig 16 21a Clicker question At a specific area of a chromosome the sequence of nucleotides below is present where the chain opens to form a replication fork 3 C C T A G G C T G C A A T C C 5 An RNA primer is formed starting at the underlined T T of the template Which of the following represents the primer sequence A 5 G C C T A G G 3 B 3 G C C T A G G 5 C 5 A C G T T A G G 3 D 5 A C G U U A G G 3 Reminder homework due Wednesday 12PM based in part on independent reading No class or sections or OH on Monday check the website Announcements for days times of makeup sections and OH Today explaining ideas to your nearest neighbors The



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