04/06/06 BCMB 8020 Spring 2006 C127 Life Sciences Building Tuesdays & Thursdays (12:30-3:15) Carbohydrates: Structure, Function, Biosynthesis Debra Mohnen Department of Biochemistry and Molecular Biology Complex Carbohydrate Research Center 542-4458 [email protected] WEB SITE: http://www.ccrc.uga.edu/personnel/dmohnen/list.html Important Information!! You will be asked to carry out several “in class” activities in a group. You should use the same groups that you used with Dr. Schmidt. To confirm the groups, you will be asked to give Dr. Mohnen a list of all group members before the end of class on Thursday, April 6. Due before class, April 11 1. Read Chapter 7: pages 356-381 and Chapter 23 pages 852-862 in the class text (Biochemistry, third Edition by Voet and Voet, 2004, Wiley). 2. Read the articles by Rudd et al., 2004; Shearer and Graham (2004); and James et al., 2003. These articles will be given out in class. Pdf files of additional optional articles can be found on the website http://cell.ccrc.uga.edu/~dmohnen/bcmb8020/list.html 3. Required PDF files will be available on the website at least two days before class (http://cell.ccrc.uga.edu/~dmohnen/bcmb8020/list.html). Be sure to check the web site regularly.04/06/06 BCMB 8020 Spring 2006 C127 Life Sciences Building Tuesdays & Thursdays (12:30-3:15) Carbohydrates: Structure, Function, Biosynthesis Debra Mohnen Apr 6 CARBOHYDRATES: General Review Apr 6 Overview Apr 11 Analytical methods / Energy & storage carbohydrates Apr 11 Starch / Glycogen Apr 13 Nucleotide sugars / carbohydrate transport / glycosyltransferases Apr 13 N-linked Glycoproteins / biosynthesis Apr 18 O-linked Glycoproteins / biosynthesis Apr 18 Glycosaminoglycans and proteoglycans Apr 20 Extracellular nonstandard O-glycans / congenital muscular dystrophy (Lance Wells) Apr 20 Intracellular O-glycans in disease / diabetes (Lance Wells) Apr 25 Bacterial cell wall and function (Russell Carlson) Apr 25 Fungal cell wall polysaccharides Apr 27 Plant cell wall polysaccharides Apr 27 Bioactive oligosaccharides/carbohydrate-protein interactions May 4 FINAL EXAM (12:00-3:00; covers lectures April
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