IUB PHSL-P 215 - Lab #6: Neurophysiology Simulation (11 pages)

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Lab #6: Neurophysiology Simulation



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Lab #6: Neurophysiology Simulation

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Pages:
11
School:
Indiana University, Bloomington
Course:
Phsl-P 215 - Basic Human Physiology

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Lab 6 Neurophysiology Simulation Background Neurons Fig 6 1 are cells in the nervous system that are used conduct signals at high speed from one part of the body to another This enables rapid precise responses to occur in order to compensate for changes in the environment Neurons are able to send signals at high speed due to their ability to generate and conduct an electrical signal called an action potential down the length of their axons An action potential is a brief reversal of the membrane potential so that for a brief interval at a segment of the axon the intracellular fluid just inside of the plasma membrane is more positive than is the extracellular fluid just outside the plasma membrane This signal is typically generated at the axon hillock of the neuron and requires the opening of voltage gated ion channels specialized pore like transmembrane proteins that open to allow ion passage in response to changes in the relative charge difference across the plasma membrane There are two different types of voltage gated ion channels important for the generation action potentials those specific for sodium ion Na and those specific for potassium ion K In the intervals between action potentials i e when the neuron is resting the two types of ions are kept at different concentrations across the plasma membrane Fig 6 2 Na is maintained at higher concentrations outside the cell than inside the cell Conversely K tends to be accumulated at higher concentrations inside the cell than outside the cell The potential for movement of these ions across the cell membrane is thus influenced by the Dendrites Schwann Cells Axon Terminals Axon Hillock Nucleus Cell Body Axon Fig 6 1 Illustration of a neuron and its major associated structures Figure 6 2 Distribution of ions across the plasma membrane during resting potential Different font sizes for Na and K indicate differences in relative concentration concentration gradients for each ion Moreover charge differences across the cell



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