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UNC-Chapel Hill BIOL 202 - Biol 202 Syllabus

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Molecular Biology and GeneticsBIOL 202, Summer Session II: 2009Class Information:Instructors:Dr. Tonya Laakko Train Gina PanasikOffice Hours: M-Th 11:15-12:45 Office Hours: T and Th 11:15-12:45 andand by appointment by appointmentCourse Description:This course will explore the structure and function of nucleic acids, principles of inheritance, gene expression and genetic engineering.Required Text:Additional Requirements:Exams: Semester exams will utilize a variety of question formats. There will be true/false, multiple choice, fill-ins and short answer questions.Final Exam: The final exam will be cumulative and will consist of true/false and multiple choice questions.Recitation: The grade for the recitation portion of this course will be comprised of graded assigned problems and in-class group work.Lecture OutlineMolecular Biology and Genetics BIOL 202, Summer Session II: 2009 Class Information: Lecture: M-F, 9:45-11:15 a.m., Wilson Hall 107 Recitations: Monday, Tuesday and Thursday 12:00-12:50 p.m. (601) or 1:00-1:50 p.m. (602) Website: http://blackboard.unc.edu/ Instructors: Dr. Tonya Laakko Train Gina Panasik Office: Wilson Hall G11 Office: Wilson Hall G11 Contact: [email protected] Contact: [email protected] Office Hours: M-Th 11:15-12:45 Office Hours: T and Th 11:15-12:45 and and by appointment by appointment Recitation Instructor: Deepak Gopalakrishna : [email protected] Supplemental Instruction: Lauren Bauer: [email protected] Course Description: This course will explore the structure and function of nucleic acids, principles of inheritance, gene expression and genetic engineering. Required Text: Introduction to Genetic Analysis, 9th Edition, W.H. Freeman & Co. by Griffiths, Wessler, Lewontin, and Carroll Web-based bioinformatics tutorials, animations, and other supplemental information can be found at http://bcs.whfreeman.com/iga9e/ Additional Requirements: • Prerequisites are a grade of C or higher in BIOL 101 and CHEM 101 or CHEM 102 • Students will be required to utilize Blackboard™ (Bb) to obtain assignments and other information. • You must be accessible at the email address listed in Bb. • You must bring a calculator (cell phones may not be used as calculators) to each exam. Course Policies: • Attendance- It is to your benefit to attend each lecture and recitation session. This course will move quickly and cover a lot of material. If you fall behind it will be a significant disadvantage. With that said, there is no formal penalty for absences from lecture. Absences from recitation will result in a forfeit of any points earned during the session (including homework problems).• Missed Exams- You may NOT make-up missed exams. The rare exception to this policy is in the case of a University-approved absence or a documented emergency. • Integrity- Lying, cheating or stealing will not be tolerated. You are bound by the University Honor Code and any violation will be reported to the Honor Court. During examinations, the only electronic device allowed is a calculator. All other electronics must be stowed. During class, texting, twittering, Facebooking… is disrespectful, please refrain from e-communicating. Special Needs: Please contact an instructor as soon as possible to discuss any documented special needs. We will do everything possible to make accommodations for your success in this class. The website for the Academic Success Program for Students with Learning Disabilities can be found at http://www.unc.edu/depts/lds/. Grading: Point distribution Percent of grade Semester exams (100 points each) 300 points 60 % Final Exam (cumulative) 150 points 30 % Recitation (homework/participation) 50 points 10 % The grading scale is as follows: A 93-100% C+ 77-79.9 D- 60-62.9 A- 90-92.9 C 73-76.9 F <60 B+ 87-89.9 C- 70-72.9 B 83-86.9 D+ 67-69.9 B- 80-82.9 D 63-66.9 A = superior performance, B = good performance, C = average performance, D = below average performance, F = failure Exams: Semester exams will utilize a variety of question formats. There will be true/false, multiple choice, fill-ins and short answer questions. Final Exam: The final exam will be cumulative and will consist of true/false and multiple choice questions. Recitation: The grade for the recitation portion of this course will be comprised of graded assigned problems and in-class group work.Lecture Outline Date Topic Reading Instructor Thurs 06/18 DNA as genetic material Ch 1, section 1.2, Ch 2, section 2.1, Ch 7, intro, sections 7.1-7.3 TLT Fri 06/19 DNA replication Ch 7, sections 7.4-7.7 TLT Mon 06/22 DNA transcription and RNA processing Ch 8, intro, sections 8.1-8.4 TLT Tues 06/23 Protein synthesis Ch 9, intro, sections 9.1-9.6 TLT Wed 06/24 Protein synthesis Ch 9, intro, sections 9.1-9.6 TLT Thurs 06/25 Prokaryotic regulation of gene transcription Ch 10, intro, sections 10.1-10.3 TLT Fri 06/26 Exam 1 TLT Mon 06/29 Eukaryotic regulation of gene transcription Ch 11, intro, sections 11.1-11.4 TLT Tues 06/39 Mutations Ch 15, intro, sections 15.1-15.3, 15.6 TLT Wed 07/01 Recombinant DNA technology Ch 20, intro, sections 20.1-20.2 TLT Thurs 07/02 Recombinant DNA technology Ch 20, sections 20.3 and 20.6 TLT Fri 07/03 HOLIDAY Mon 07/06 Inheritance: Review of Mitosis and Meiosis, Single gene crosses Ch. 2 pp. 37-61 GP Tues 07/07 Inheritance: X-linked inheritance and pedigrees Ch. 2 pp. 61-76 GP Wed 07/08 Exam 2 GP/TLT Thurs 07/09 Inheritance: Independent Assortment of Two Genes (Two-gene crosses) Ch. 3 pp. 89-106 GP Fri 07/10 Genetic recombination: Recombination, Linkage, Mapping Ch. 3 pp. 106-109 Ch. 4 pp. 129-140 GP Mon 07/13 Genetic Recombination: Recombination, Linkage, Mapping Ch. 4 pp. 140-143 GP Tues 07/14 Gene Interaction Ch. 6 pp. 221-230 pp. 235-249 GP Wed 07/15 Mutation: Chromosome Mutations Ch. 16 pp. 555-586 GP Thurs 07/16 Stem Cell, Reproductive Cloning and Therapeutic Cloning .pdf file(s) will be posted on BB GP Fri 07/17 Exam 3 GP Mon 07/20 Forensics and Genetic Counseling Websites will be listed on BB GP Tues 07/21 Review day GP Thurs 07/23 Final Exam 8-11 a.m. GP/TLTRECITATION ASSIGNMENTS The following are homework assignments to be turned in and reviewed in recitation. Solving chapter problems might be your best out-of-class tool for comprehending the


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UNC-Chapel Hill BIOL 202 - Biol 202 Syllabus

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