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Finite Element Analysis from Cardiac Magnetic Resonance Imaging



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Mitral Valve Modelling in Ischemic Patients Finite Element Analysis from Cardiac Magnetic Resonance Imaging Carlo A Conti1 Marco Stevanella1 Francesco Maffessanti1 Salvatore Trunfio2 Emiliano Votta1 Alberto Roghi2 Oberdan Parodi2 3 Enrico G Caiani1 Alberto Redaelli1 1 Politecnico di Milano Milano Italy Niguarda Ca Granda Hospital Milano Italy 3 CNR Institute of Clinical Physiology Pisa Italy 2 Abstract The goal of the present work was to develop a framework for the analysis of time varying mitral valve MV geometry from cardiac magnetic resonance CMR imaging and to integrate these data in a patient specific simulation of MV closure CMR imaging of 18 long axis planes was performed on a healthy subject and on two ischemic patients with MV regurgitation MV annulus geometry leaflets surface and papillary muscles position were obtained using custom software Hyperelastic anisotropic mechanical properties were assigned to the MV tissues and a pressure load curve was applied to the leaflets Results concerning healthy MV biomechanics were consistent with previous computational data Ischemic MV models appear suitable to mimic the pathological malfunctioning of the valve The proposed models could constitute the basis for the planning of surgical procedures 1 Introduction Ischemic mitral regurgitation IMR is a common and important complication of ischemic heart disease associated with excess mortality independently of baseline characteristics and degree of ventricular dysfunction 1 Because altered annular geometry often contributes to leaflet malcoaptation in ischemic mitral regurgitation surgical correction is required to restore proper MV function Current standard treatment for IMR is the implantation of an annuloplasty ring that downsizes the mitral annulus to increase leaflet coaptation However residual or recurrent mitral regurgitation frequently appears after ring annuloplasty as a consequence of a poor prognosis 2 Thus models for predicting surgical outcomes of these



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