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Week 8, Session 2The Cell Cycle Supplemental InstructionIowa State UniversityLeader: KelseyCourse: Bio 211 (5)Instructor: Dr. HolscherDate: 10-15-091. What differentiates living matter from non-living matter?Living matter is able to reproduce their own kind.2. What is continuity of life based on?The reproduction of cells3. What is the function of mitosis in animal cells? (What is produced?)To produce 2 identical daughter cells from 1 parent cell4. In humans, ____somatic_______________ cells have 46 chromosomes, and ___reproductive___________cells have 23 chromosomes. 5. The genetic info, packaged as DNA, is called the ___genome________________. 6. Label the diagram:7. Eukaryotic cell division consists of _mitosis_____________ and __cytokinesis_______. 8. What phase alternates with the mitotic phase of eukaryotic cell division?interphase9. What are the three stages of interphase?  G1 S G210. What is G0 stage? How do cells get here? What kinds of cells might we find in this stage? G0 is a “no growth” stage. Cells get here by not receiving a signal during G1 to continue growing. We would find cells in this stage that don’t divide often: muscle, skeletal, and Supplemental Instruction1060 Hixson-Lied Student Success Center v 294-6624 v www.si.iastate.educentromeresister chromatidchromosomenerve cells are some examples. 11. What are the five phases of the mitotic cycle? Describe each phase:  Prophase: early mitotic spindles form Prometaphase: centrosomes are present at opposite ends of the cell, nuclear envelope disintegrates Metaphase: all chromosomes line up at the metaphase plate Anaphase: chromosomes separate, cell elongates Telophase: chromosomes elongate/unravel, cleavage furrow forms, nuclear envelope re-forms12. What two regulatory proteins are involved in cell cycle control? How do they work together? Cyclins and cyclin-dependent kinases (CDKs). CDKs are usually present, but inactive. CDKs become activated by binding to cyclins (thus the name cyclin DEPENDENT kinase). 13. What are examples of external signals that control cell cycle checkpoints? chemical signals: growth factors (PDGF) stimulate other cells to dividephysical signals: density-dependent inhibition and anchorage-dependent inhibition14. What inhibitions do cancer cells lack?Cancer cells lack both physical signals (density-dependent and anchorage-dependent)15. Explain the difference between a tumor being benign and malignant.benign: tumors are cancerous but confined to one areamalignant: tumors invade surrounding tissues and spread16. What does it mean to metastasize? to move/spread to other


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ISU BIOL 211 - session_3_with_answers

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