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UK IBS 605 - IBS 605 Syllabus

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IBS 605EXPERIMENTAL GENETICSFall 2010 SYLLABUSA: 90-100%B: 80- 89.9%C: 70- 79.9%D: 60- 69.9%E: below 60 %H. BLACKBOARD AND COURSE INFORMATION (IMPORTANT!)Blackboard, a software program designed for facilitating course administration, will be used this semester in IBS605. You must be able to access the Blackboard course site in order to view such items of importance as posted lecture notes, assignments (study questions, room assignments for exams) and other announcements. You can reach and register with Blackboard from the IBS site ( Steve Evans will be assisting the course director in maintenance and control of the Blackboard site for IBS605. Any questions about use of Blackboard should be directed to Steve (phone: 323-2454; e-mail: [email protected]).I. DISCUSSION/BIOINFORMATICS SESSIONSAttendance at these sessions is required and all students will be expected to participate actively in discussions. You will be expected to read assigned papers prior to class, and participate in the group discussion; details will be provided at a later date.Important: Do not use the library for printing course materials!!!J. SCHEDULEIBS 605EXPERIMENTAL GENETICSFALL 2010 SYLLABUSFaculty Department Office PhoneE-mailCourse DirectorB. T. Spear Micro, Immuno, & Molec. Gen. Combs 210257-5167 [email protected] Course FacultyR. J. Craven Molec. Pharmacology 213 Combs323-3832 [email protected] J. N. Davidson Micro, Immuno, & Molec. Gen. 304 Combs323-5207 [email protected] J. D’Orazio Pediatrics/Toxicology 204 Combs323-6238 [email protected] C. Kaetzel Micro, Immuno, & Molec. Gen. 203 Combs257-6573 [email protected] T. McClintock Physiology MS585 Willard323-1083 [email protected] M.P. Murphy Molec. & Cell. Biochemistry 211 Sanders-Brown257-1412 x490 [email protected] R. D. Perry Micro, Immuno, & Molec. Gen. MN362 Willard323-6341 [email protected] A. COURSE DESCRIPTIONIBS605 is a 3 credit hour course designed to provide first year graduate students with the foundation of knowledge in classical and molecular genetics necessary for advanced graduate courses and research in any of the basic science departments of the UK College of Medicine. The course will be focused primarily on basic genetic principals, prokaryotic genetics, eukaryotic genetics, and genomics. The course will also cover contemporary topics including human genetics and bioinformatics. In addition, experimental approaches in genetic research will be reviewed. Course material will be presented in several formats, primarily of didactic lecture by expert faculty, but will also be reinforced by discussions of selected readings and bioinformatics small-group sessions. Lectures will be given Monday, Wednesday, and Friday from 10:00 - 10:50 AM in MN463 of the ChandlerMedical Center. Location of the Bioinformatics sessions (Dec. 6/8/10) is to be determined. ALL IN-CLASS EXAMS WILL TAKE PLACE IN THE HOSPITAL AUDITORIUM (HG611) AT THE DESIGNATED TIMES; THE FINAL EXAM WILL BE HELD ON FRIDAY, DEC. 17 FROM 10:30AM - 12:30 PM AT A LOCATION TBD.B. COURSE OBJECTIVESThe primary objective of this course will be to provide graduate students with a working knowledge of basic principles and the latest advances in areas of contemporary genetic research. C. TEXT Genetics - from genes to genomes, 3nd Edition, Hartwell, et al., McGraw- Hill, NY, 2008. A copy will be held in reserve and available in the Medical Center Library)Additional readings from the scientific literature will also be provided, or will be readily accessible from on-linescientific journals and the course website.1D. PREREQUISITESGeneral College Chemistry I and II, Organic Chemistry I and II, Principles of Biology I and II or equivalents. Students who have questions whether they can enroll in IBS605 should talk with the course director.E. GRADINGStudents will be evaluated based on: 1) performance on four written examinations, 2) performance in homework assignments and bioinformatics group session. Each exam will last approximately two hours and each will account for 21% of the final grade (Total = 84% of Final Grade). The Final Exam is NOT cumulative. Locations for exams are listed above and in syllabus, will be announced in class, and posted on Blackboard course website (see below). Another component of the final grade will be performance on problem sets that will accompany papers for discussion (5 problems sets @ 2% each = 10% of Final Grade) and the bioinformatics session (6% of Final Grade). Unless the course director is notified ahead of time, failure to turn in assignments on due date or lack of attendance at bioinformatics sessions will result in a grade of zero for these events. The grading standards to be employed for the course are as follows:A: 90-100%B: 80- 89.9%C: 70- 79.9%D: 60- 69.9%E: below 60 %Students who perform in these ranges will be guaranteed to receive the indicated grades, at a minimum. However, some adjustments (curving) of this scale are possible, depending on the performance of the class as a whole. Grades will NOT be rounded up.Challenges to a grade can be submitted for a reevaluation if it is deemed that a mistake has been made in the original grading. Challenges must be accompanied by a written explanation of the perceived mistake. Upon submission of a challenge, the entire examination will be subject to reevaluation and all questions therein will be re-graded. Examinations for re-grading must be submitted within one week (7 days) and to the course director only.Graduate students will not receive a grade of “D” but instead will receive a failing mark for an average under 70%. All examinations must be taken at the scheduled time except when legitimate medical or personal circumstances make it impossible to do so. The course director must be notified of the circumstances of your absence prior to the examination. In these cases, either an oral or written make-up examination will be given. An “I” grade will not be assigned to students who simply miss an examination.2F. UNDERGRADUATE ENROLLMENTUndergraduate students may enroll in the course with the permission of the course director and the Graduate School. G. OFFICE HOURSThe course director and instructors will be available for consultation. Students are encouraged to consult with participating faculty as needed. It is suggested to call or email faculty to set up an appointment as specific office hours are not established.H.

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