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UW-Madison BME 300 - MRI Fat Quantification Phantom

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MRI Fat Quantification Phantom Client: Dr. Scott B Reeder Medical Physics and Radiology Phone: (608) – 265-9964 Email: [email protected] Dr. Walter F Block Biomedical Engineering and Electrical Engineering Phone: (608) 265-9686 Email: [email protected] Catherine D G Hines Radiology Phone: (608) 265 – 9688 Email: [email protected] Team: Bogdan Dzyubak (Team Leader) Joe Helfenberger (BSAC) Nick Balge (BWIG) Matt Parlato (Communicator) Progress Report for November 5 – November 12 Problem Statement: The goal of this project is to develop an MRI phantom for the quantification of fat. This phantom will be used to test MRI techniques developed by the client for the imaging of fat in vivo. The phantom must contain samples of known physiologically relevant quantities of fat. The eventual purpose is quality control of MRI scanners that use fat-water contrast imaging. This Week’s Goals: o Begin manufacturing the honeycomb o Begin measuring the fat/water fractions and make the emulsions o Send the paperThis Week’s Accomplishments: o Finished the honeycomb o Began working on fat/water emulsions. More animal hide gel than initially thought needs to be used to make the emulsions stable. A greater quantity of it will need to be purchased o Finished composing the paper draft, including the predicted results section, and sent it to Dr. Chesler for review o Performed calculations of airflow through the vials and necessary ratios of holes on the two sides of the vial holder; as was predicted, the only limitation on size and shape of the holes are those of practical, manufacturing nature Next Week’s Goals: o Continue making the emulsions o Take the first scan of the honeycomb, water and oil references, and whatever emulsions are available o Figure out the Gadolinium doping principles, make the calculation and arrange for some Gadolinium. Project Difficulties: o No significant difficulties this week.Team Activities Date Members Activity Time Spent 11/06/09 Team Team meeting 0.5 hr 11/07/09 Nick, Joe Air escape calculations 0.5 hr 11/07/09 Nick Preparation for vial mixing 11/07/09 Joe Air escape calculations 6 hr 11/07/09 Joe Research on emulsion components 2.5 hr 11/07/09 Joe Vial drawings in Solidworks 2 hr 11/07/09 Joe, Nick Creating emulsions 1.75 hr 11/07/09 Matt Machining the UHMWPE block 2 hr 11/08/09 Bogdan Work on the paper 2.5 hr 11/08/09 Matt Machining the UHMWPE block 4 hr 11/08/09 Bogdan, Matt Discussion of necessity of accuracy of the airflow calculation 1 hr 11/10/09 Bogdan Reviewing the paper 2 hr 11/09/09 Matt Read over the paper 1.5 hr 11/09/09 Nick Creating emulsions 1.25 hr 11/10/09 Joe, Nick Expected results section 1.5 hr 11/10/09 Nick More work on paper 1.5 hr 11/10/09 Bogdan Meeting with Dr. Block to schedule the first scan 0.5 hr 11/10/09 Joe Updated Solidworks drawings 1.75 hr 11/10/09 Matt, Joe Emulsion planning 0.5 hr 11/11/09 Bogdan Attempted visit and email to Catherine 0.5 hr 11/11/09 Bogdan Writing progress report 0.5 hrProject Schedule Task September October November December 3 10 17 24 1 8 15 22 29 7 14 21 28 5 12 17 Project Development Research Brainstorm/Design Development Finalize Design Prototyping Order Supplies Deliverables Progress Reports Mid-semester Presentation (10/16) * Writing Final Report Final Report (12/11) * Final Poster (12/4) * Meetings Client Advisor Website Online * = deliverable due Future Timeline Task October November December __ 7 14 21 28 5 12 Project Development Brainstorm/Design Development Finalize Design Prototyping Testing Order Supplies Deliverables Draft Paper Finalize Paper Prepare Poster Submit Paper (12/11) * Present Poster (12/4) *Expenses Ultra High Molecular Weight Polyethelene (UHMWPE) - $43.75 Clear Glass Vials - $83.72 Animal Hide Gel – $26.71 Ivory Hand Soap – $8 Formaldehyde – $23.01 Acrylic Tank (Lock & Lock Box) – $9.99 Safflower Oil - $6.99 Total:


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UW-Madison BME 300 - MRI Fat Quantification Phantom

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