HYPOTHERMIA Brochure 3-3-10


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Hypothermic Robotic Prostatectomy Cooling to prevent surgical injury COMPLETELY NOVEL TECHNIQUE FOR REDUCING INFLAMMATION INJURY TO THE BLADDER SPHINCTERS AND NERVES FOR SEXUAL FUNCTION Technique Hypothermic cooling and improvement in urinary continence Prior work by Dr Ahlering and his associates formed the basis for a better understanding into the mechanisms responsible for delaying return of urinary and sexual following surgery see next section If a surgeon performs ideally and avoids any injury to the sexual nerves and the sphincters responsible for urinary control still most men take weeks to months to recover There is much evidence to suggest that the normal trauma of surgery plays a major role in this problem Drs Ahlering and Finley have taken well established lessons from cardiac and neurosurgeons in using cooling to stop the inflammatory cascade common to all surgical procedures Think of it as icing or not one s ankle immediately upon severely spraining it Actually we can preemptively cool the region before the injury occurs Hence HYPOTHERMIC robotic prostatectomy We devised an endorectal cooling balloon pictured above to locally cool the pelvic region to 60 68oF The cooling balloon is placed and Age of Men vs Pad Free at One Year 120 100 P value 001 87 96 Not Cooled 100100 90 97 Cooling 97 92 86 80 73 BACKGROUND RESEARCH FROM UCI HAS LEAD TO A BETTER UNDERSTANDING OF MECHANISMS WHICH APPEAR TO INHIBIT RETURN OF SEXUAL FUNCTION Since 2002 when we started our program we have published multiple scientific 9 peer reviewed papers laying the ground work leading to hypothermia Our first 3 publications dealt with the damage to nerves from thermal energy heat and how to avoid it However we learned that thermal energy did not kill the nerve but rather injured it This injury is recoverable as long as the nerve sheath is still intact However even when we avoided thermal injury there was evidence of a stretch injury With stretch injury some men recovered within 2 3

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