EVERGREEN INS 2008 - How to create a unique environment

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How to create a unique environment?Insert proteins in membrane that cantransport molecules into cells.Do membrane proteins affect ion/molecule permeability?3 classes of membrane proteins• Ionophore Channels• Transporters• pumpsElectrochemical gradients across membranesIonophore- an ion moverFacilitated diffusion via a channel proteinH+, K+Glucose transporterKasahara and HinkleFacilitated DiffusionGlucose + ATP ----> Glucose-6-P + ADPGroup Translocation SystemsActive Transport(Pumps)Active Transport Mechanisms• Major facilitator superfamily of transport proteins• ABC (ATP binding cassette) transporter systems Move molecule against its concentration gradient One or more membrane proteins required Require an expenditure of energyEnergy- electrochemical energy (proton motive force)ABC (ATP binding cassette) transporter


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EVERGREEN INS 2008 - How to create a unique environment

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